Wohlrab J, Kreft B
Universitätsklinik und Poliklinik für Dermatologie und Venerologie, Martin-Luther-Universität Halle-Wittenberg, Ernst-Grube-Str. 40, 06097, Halle (Saale), Deutschland.
An-Institut für angewandte Dermatopharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle (Saale), Deutschland.
Hautarzt. 2018 Oct;69(10):857-869. doi: 10.1007/s00105-018-4265-8.
Although primary hyperhidrosis is a common disease, secondary symptomatic hyperhidrosis is rather rare. Primary hyperhidrosis is a complex neuropathic dysregulation with a genetic predisposition and is diagnosed when patients show pathologic sweating patterns and excessive sweating for at least 6 months and fulfill at least four of the following criteria: affected areas are axillae and/or palms and/or soles and/or forehead; symmetry; no night sweating; at least once a week; onset before the age of 25; positive family history; negative impact on daily activities. Frequently used therapies are topical aluminum salts and anticholinergics, iontophoresis in water, and intracutaneous botulinum toxin. Anticholinergics are also used as systemic treatment. Surgical procedures are used as a last result. Furthermore procedures using thermolysis have been developed.
尽管原发性多汗症是一种常见疾病，但继发性症状性多汗症却相当罕见。原发性多汗症是一种具有遗传易感性的复杂神经调节失调疾病，当患者出现病理性出汗模式且多汗至少持续6个月，并满足以下至少四项标准时可确诊：受累部位为腋窝和/或手掌和/或脚底和/或额头；对称性；无夜间盗汗；每周至少一次；发病年龄在25岁之前；家族史阳性；对日常活动有负面影响。常用的治疗方法有局部使用铝盐和抗胆碱能药物、水中离子电渗疗法以及皮内注射肉毒杆菌毒素。抗胆碱能药物也用作全身治疗。手术程序作为最后的手段使用。此外，已经开发出了使用热分解的程序。
