Liver Surgical Unit, Agia Olga Hospital, Athens, Greece.
HPB (Oxford). 2006;8(4):255-63. doi: 10.1080/13651820500273673.
This article reviews the current results of radiofrequency application in the management of hepatocellular carcinoma (HCC) with reference to the comparison between the different surgical modalities.
An electronic search was performed for studies on the treatment of HCC.
Thermoablation by means of radiofrequency (RFA), microwave coagulation therapy (MCT) and laser-induced thermotherapy (LITT) provides tumor necrosis with a low complication rate. These methods are still not predictable and it is difficult to monitor the extent of necrosis in a real-time manner. Combined transarterial embolization and RF ablation is a promising strategy for large HCCs. Radiofrequency-assisted liver resection is unique and has become very popular recently because it permits parenchymal transection with minimal blood loss.
Many alternative techniques have been applied recently for the management of HCC but their exact roles need to be defined by randomized studies. Advances in technology and refinements in technique may provide an effective and predictable way to ablate liver tumors using radiofrequency devices.
本文通过对不同手术方式的比较，综述了射频应用于肝细胞癌（HCC）治疗的现状。
对 HCC 治疗的研究进行了电子检索。
射频（RFA）、微波凝固疗法（MCT）和激光诱导热疗（LITT）等热消融技术可使肿瘤发生坏死，且并发症发生率低。但这些方法仍不可预测，难以实时监测坏死范围。联合经动脉栓塞和射频消融治疗是治疗大 HCC 的一种很有前途的策略。射频辅助肝切除术是一种独特的方法，最近非常流行，因为它可以在最小出血的情况下进行肝实质离断。
目前已经有许多替代技术被应用于 HCC 的治疗，但需要通过随机研究来明确其确切作用。技术的进步和技术的改进可能为使用射频设备消融肝肿瘤提供一种有效且可预测的方法。
