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Malaria combination therapies: advantages and shortcomings.

作者信息

Martinelli A, Moreira R, Ravo P V L

机构信息

Centro de Malária e Outras Doenças, Tropicais/IHMT/UEI Biologia Molecular, Rua da Junqueira 96. 1349-008 Lisbon, Portugal.

出版信息

Mini Rev Med Chem. 2008 Mar;8(3):201-12. doi: 10.2174/138955708783744092.

Abstract

Drug combination therapies have been devised to delay the development and spread of resistant malaria parasites. However, poor design often leads to ineffective combinations. Here, the properties of various drug combinations are reviewed in relationship to drug resistance and their pharmacokinetic compatibility.

摘要

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