Williamson R M, Haines J
Department of Anaesthesia, Macclesfield District General Hospital, Victoria Road, Macclesfield SK10 3BL, UK.
Anaesthesia. 2008 Apr;63(4):385-8. doi: 10.1111/j.1365-2044.2007.05349.x.
There is evidence that administration of lipid emulsion improves outcome in cardiovascular collapse secondary to local anaesthetic toxicity. We sent a questionnaire to the lead consultant anaesthetist in every consultant-led labour ward in the UK asking about local guidelines for treatment of cardiac arrest, and whether or nor lipid emulsion was available on the labour ward and included in the guideline. We received replies from 195 (86%) labour wards. One hundred and seven (55%) reported having a guideline for the treatment of cardiovascular collapse secondary to local anaesthetic toxicity. Of these guidelines, lipid emulsion was included in 78 (40%). Lipid emulsion was readily available on 95 labour wards (49%). Of the remaining units, there were plans to make lipid available in the near future in 46 (46%). Of the 95 labour wards where lipid emulsion was readily available, 80 (84%) had a recommended dose regimen for its administration. Around three-quarters of labour wards in the UK either have lipid emulsion available or plan to obtain it. This uptake should ideally be 100%.
有证据表明,输注脂质乳剂可改善局部麻醉药中毒继发的心搏骤停患者的预后。我们向英国每个由顾问主导的产科病房的首席麻醉顾问发送了一份问卷,询问有关心脏骤停治疗的当地指南,以及产科病房是否有脂质乳剂并将其纳入指南。我们收到了195个(86%)产科病房的回复。107个(55%)报告有局部麻醉药中毒继发的心搏骤停治疗指南。在这些指南中,78个(40%)纳入了脂质乳剂。95个产科病房(49%)有脂质乳剂。在其余病房中,有46个(46%)计划在不久的将来提供脂质乳剂。在95个有脂质乳剂的产科病房中,80个(84%)有推荐的给药剂量方案。英国约四分之三的产科病房要么有脂质乳剂,要么计划获取脂质乳剂。理想情况下,这一使用率应为100%。