Blomstedt P, Tisch S, Hariz M I
Department of Neurosurgery, University Hospital of Northern Sweden, Umeå, Sweden.
Acta Neurol Scand. 2008 Sep;118(3):198-202. doi: 10.1111/j.1600-0404.2008.00999.x. Epub 2008 Mar 11.
Pallidal deep brain stimulation (DBS) of globus pallidus internus (Gpi) has emerged as an effective treatment for dystonia. The experience is however limited concerning focal dystonias and to date only a few cases of pallidal DBS in the treatment of Meige syndrome have been published.
METHODS/RESULTS: We here present a patient with Meige syndrome in whom unilateral pallidal DBS failed to improve the axial symptoms, but bilateral stimulation resulted in a major improvement. The Burke-Fahn-Marsden score (BFM) improved by 71.5% and the patient's blepharospasm was abolished.
The results suggest bilateral pallidal DBS may be an effective treatment for Meige syndrome.
苍白球内侧部（Gpi）的苍白球深部脑刺激（DBS）已成为治疗肌张力障碍的有效方法。然而，关于局灶性肌张力障碍的经验有限，迄今为止，仅有少数苍白球DBS治疗Meige综合征的病例发表。
方法/结果：我们在此报告一名Meige综合征患者，单侧苍白球DBS未能改善轴性症状，但双侧刺激导致显著改善。伯克-法恩-马斯登评分（BFM）提高了71.5%，患者的眼睑痉挛消失。
结果表明双侧苍白球DBS可能是治疗Meige综合征的有效方法。
