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所罗门群岛孕期疟疾:预防与控制的障碍

Malaria in pregnancy in the Solomon islands: barriers to prevention and control.

作者信息

Appleyard Bridget, Tuni Makiva, Cheng Qin, Chen Nanhua, Bryan Joan, McCarthy James S

机构信息

The Australian Centre for International and Tropical Health, a joint program of the Queensland Institute of Medical Research, Herston, Australia.

出版信息

Am J Trop Med Hyg. 2008 Mar;78(3):449-54.

Abstract

A study of malaria in pregnancy (MIP) was undertaken in Marovo Lagoon, Solomon Islands, to evaluate pregnancy-specific control strategies for malaria. Peripheral parasitemia was present in 18% (19/106) of women: 15 Plasmodium falciparum and 4 P. vivax. Primigravidae were twice as likely to be parasitemic as multigravidae (31% versus 14%; relative risk: 2.24; 95% confidence interval: 1.01-4.96; P = 0.05). Although ante-natal clinic attendance was high, women booked late (mean, 19.7 weeks) and attended irregularly. Free insecticide-treated nets (ITN) were not distributed despite government policy. Primigravidae were less likely to have an ITN in their homes than multigravidae (relative risk: 2.13; 95% confidence interval: 1.03-4.40). Coverage with chloroquine prophylaxis was low. This study revealed barriers to control of MIP at both the health service and client level. To develop an evidence-based malaria control policy in pregnancy for this region, further study of the epidemiology of malaria and its effects, including social and behavioral aspects, is needed.

摘要

在所罗门群岛的马罗沃泻湖开展了一项关于妊娠疟疾(MIP)的研究,以评估针对疟疾的妊娠特异性控制策略。18%(19/106)的女性存在外周血寄生虫血症:15例为恶性疟原虫,4例为间日疟原虫。初产妇出现寄生虫血症的可能性是经产妇的两倍(31%对14%;相对风险:2.24;95%置信区间:1.01 - 4.96;P = 0.05)。尽管产前诊所就诊率很高,但女性登记就诊较晚(平均19.7周)且就诊不规律。尽管有政府政策,但免费的经杀虫剂处理的蚊帐(ITN)并未分发。初产妇家中拥有ITN的可能性低于经产妇(相对风险:2.13;95%置信区间:1.03 - 4.40)。氯喹预防的覆盖率较低。这项研究揭示了在卫生服务和客户层面控制妊娠疟疾的障碍。为了为该地区制定基于证据的妊娠疟疾控制政策,需要进一步研究疟疾的流行病学及其影响,包括社会和行为方面。

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