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不重建肝中静脉的成人右叶活体肝移植:一项109例的单中心研究

Adult right lobe live donor liver transplantation without reconstruction of the middle hepatic vein: a single-center study of 109 cases.

作者信息

Campsen Jeffrey, Hendrickson Richard J, Zimmerman Michael A, Wachs Michael, Bak Thomas, Russ Paul, Bennet William, Trotter James, Kam Igal

机构信息

Division of Transplant Surgery, University of Colorado Health Sciences Center, Denver, Colorado, USA.

出版信息

Transplantation. 2008 Mar 15;85(5):775-7. doi: 10.1097/TP.0b013e31816636ad.

Abstract

We report our experience in adult-to-adult right hepatic lobe living donor liver transplantation (ALDLT) using extension of the hepatectomy transection line medially to incorporate the right middle hepatic vein branches into the donor graft. One hundred and nine ALDLT were performed at the University of Colorado from August 1997 to December 2005. Donors were screened preoperatively for hepatic venous anatomy compatible with this technique. Of the 109 ALDLT, the first 10 did not include the right middle hepatic vein branches in the graft. As such, three patients required retransplantation, two from graft loss because of venous congestion. Of the next 99 transplants, only 11 required retransplantation and none because of venous congestion. This approach allows adequate venous outflow through the right hepatic vein more than 1 cm, which is demonstrated by the absence of graft loss from venous congestion and superior graft survival.

摘要

我们报告了在成人对成人右肝叶活体肝移植(ALDLT)中,通过将肝切除线向内侧延伸,将右肝中静脉分支纳入供体移植物的经验。1997年8月至2005年12月,科罗拉多大学共进行了109例ALDLT。术前对供体进行筛选,以确定其肝静脉解剖结构是否适合该技术。在109例ALDLT中,最初的10例移植物未包含右肝中静脉分支。因此,3例患者需要再次移植,其中2例因静脉淤血导致移植物丢失。在接下来的99例移植中,只有11例需要再次移植,且无一例是因静脉淤血。这种方法可使通过右肝静脉的静脉流出足够,超过1厘米,这可通过无静脉淤血导致的移植物丢失以及较高的移植物存活率得到证明。

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