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孢子丝菌病的单一表现形式为感染性关节炎:血清学检测血清和滑液样本辅助诊断

Infectious arthritis as the single manifestation of sporotrichosis: serology from serum and synovial fluid samples as an aid to diagnosis.

作者信息

Costa Rosane Orofino, de Mesquita Karlos Celso, Damasco Patrícia S, Bernardes-Engemann Andréa Reis, Dias Claudia Maria P, Silva Ione C, Lopes-Bezerra Leila M

机构信息

Serviço de Dermatologia, Laboratório de Micologia, Hospital Universitário Pedro Ernesto, UERJ, Rio de Janeiro, Brazil.

出版信息

Rev Iberoam Micol. 2008 Mar;25(1):54-6. doi: 10.1016/s1130-1406(08)70014-7.

Abstract

Sporotrichosis is a generally cutaneous, granulomatous, chronic and benign infection. Less frequently the disease may affect the joints. Articular involvement is usually characterized by monoarthritis in the absence of systemic symptoms, generally preceded by skin lesions, and frequently affects immunosuppressed individuals. We describe here the case of a healthy patient presenting knee arthritis without skin lesions, diagnosed as sporotrichosis, and treated with oral itraconazole. Serology used in this case was an invaluable tool for the diagnosis of sporotrichosis arthritis lacking skin lesions.

摘要

孢子丝菌病是一种通常累及皮肤的肉芽肿性慢性良性感染。该病较少累及关节。关节受累通常表现为单关节炎,无全身症状,一般先有皮肤病变,且常影响免疫抑制个体。我们在此描述一例健康患者,其出现无皮肤病变的膝关节炎,诊断为孢子丝菌病,并接受口服伊曲康唑治疗。本病例中使用的血清学检测对于诊断无皮肤病变的孢子丝菌病关节炎是一项非常有价值的工具。

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