Peters K M, Koberg K, Zwadlo-Klarwasser G, Zilkens K W
Orthopädische Klinik, Medizinischen Fakultät der RWTH Aachen.
Z Orthop Ihre Grenzgeb. 1991 Jul-Aug;129(4):313-8. doi: 10.1055/s-2008-1040247.
Investigations in patients with chronic post-traumatic osteomyelitis could demonstrate several deficits in immunologic response: Phagocytic activity of phagocytes is lowered accompanied by a functional deminution of leukocyte receptors for C3. Intracellular killing is diminished. Investigations concerning T lymphocyte subpopulations verified a decrease in total T cells and helper/inducer T cells. Dysfunctions in specific humoral immune response are still debatable.
对慢性创伤后骨髓炎患者的研究表明，免疫反应存在多种缺陷：吞噬细胞的吞噬活性降低，同时白细胞C3受体功能减退。细胞内杀伤能力减弱。关于T淋巴细胞亚群的研究证实，总T细胞以及辅助/诱导性T细胞数量减少。特异性体液免疫反应的功能障碍仍存在争议。
