Heberling H J, Gauer J, Lohmann D
Z Gesamte Inn Med. 1976 Jul 1;31(13):497-500.
The possibilities of the treatment of hyperthyroidism are mentioned, in which cases the author especially deals with the medicamentous therapy, taking into consideration the different chemical groups (imidazol derivations, thiourazil derivations, perchlorates) and their therapeutic mechanisms. The indications and contraindications of this treatment and the possible side effects are compiled in form of a table. The in-vitro-parameters which are necessary for the observation of the course are estimated in their significance. The author deals with the problems of the additional treatment. Taking into consideration indications and contraindications as well as controls of the course of functional parameters the medicamentous therapy concerned is a treatment with a good prognosis. It is promising particularly in such cases, when suitable parameters are used for the solution of the question concerning the end of the therapy. For this purpose nowadays two tests are at our disposal: 1. modified Alexander's test (radioiodine-test and suppression test under thyreostatic therapy) and 2. TRH-test with radioimmunological determination of TSH. The treatment should be carried out in adequate endocrinological dispensaries, as there are certain risks in not optimal therapy.
文中提到了甲状腺功能亢进症的治疗可能性，作者特别探讨了药物治疗，考虑了不同的化学类别（咪唑衍生物、硫脲嘧啶衍生物、高氯酸盐）及其治疗机制。该治疗的适应症、禁忌症以及可能的副作用以表格形式汇总。评估了观察病程所需的体外参数的重要性。作者探讨了辅助治疗的问题。考虑到适应症、禁忌症以及功能参数病程的监测，相关药物治疗预后良好。特别是在使用合适参数解决治疗终点问题的情况下，该治疗很有前景。为此，目前我们有两种检测方法：1. 改良亚历山大试验（放射性碘试验和甲状腺抑制疗法下的抑制试验）和2. 促甲状腺激素释放激素试验及促甲状腺激素的放射免疫测定。治疗应在合适的内分泌诊疗机构进行，因为治疗不优化会有一定风险。
