绵羊哮喘、慢性阻塞性肺疾病和囊性纤维化的建模。
Modeling of asthma, COPD and cystic fibrosis in sheep.
作者信息
Abraham William M
机构信息
Department of Research, Mount Sinai Medical Center, 4300 Alton Road, Miami Beach, FL 33140, USA.
出版信息
Pulm Pharmacol Ther. 2008 Oct;21(5):743-54. doi: 10.1016/j.pupt.2008.01.010. Epub 2008 Feb 6.
PMID:18339565
Abstract
Sheep naturally allergic to Ascaris suum antigen have been used to study the pathophysiology of asthma and more recently allergic rhinitis, chronic obstructive pulmonary disease (COPD) and cystic fibrosis. The utility of the model as it relates to the study of these diseases is discussed.
摘要
对猪蛔虫抗原天然过敏的绵羊已被用于研究哮喘的病理生理学，以及最近对过敏性鼻炎、慢性阻塞性肺疾病（COPD）和囊性纤维化的研究。本文讨论了该模型在这些疾病研究中的实用性。
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