Thiboutot Diane M, Harper Julie C, O'Connell Katharine, Rich Phoebe, Sondheimer Steven J
Pennsylvania State University College of Medicine, Hershey, USA.
Cutis. 2008 Jan;81(1 Suppl):26-31.
A roundtable was convened to examine the issues surrounding the use of hormonal therapy in the treatment of acne. Obstetrician-gynecologists (OB/ GYNs) and dermatologists often have varying views with regard to the use of oral contraceptives (OCs) and other agents in patients with acne. If polycystic ovary syndrome (PCOS), the most common hormonal cause of acne, has been diagnosed, the use of OCs is not usually disputed. Hormonal evaluation is recommended for certain conditions such as virilization. Although PCOS is often the source of the problem, it is important to rule out a testosterone-producing tumor or an adrenal tumor. It was determined, however, that the perception that OCs cause cervical and breast cancer persists among some dermatologists. Even in women with a family history of breast cancer, OCs do not increase the risk. Nor is cervical cancer related to OC use; rather, it results from human papillomavirus. Thus, patients should be assured that OCs will not increase their risk for either of these cancers. Female patients should be advised to see their gynecologists annually for breast and pelvic examinations and to discuss their concerns surrounding the use of OCs.
召开了一次圆桌会议，以探讨激素疗法治疗痤疮相关的问题。妇产科医生（OB/GYNs）和皮肤科医生对于痤疮患者使用口服避孕药（OCs）及其他药物的看法往往存在差异。如果已诊断出多囊卵巢综合征（PCOS），这是痤疮最常见的激素病因，那么使用OCs通常不会有争议。对于某些情况，如男性化，建议进行激素评估。虽然PCOS常常是问题的根源，但排除产生睾酮的肿瘤或肾上腺肿瘤很重要。然而，一些皮肤科医生仍然认为OCs会导致宫颈癌和乳腺癌。即使是有乳腺癌家族史的女性，OCs也不会增加风险。宫颈癌也与使用OCs无关；相反，它是由人乳头瘤病毒引起的。因此，应该向患者保证OCs不会增加她们患这两种癌症的风险。建议女性患者每年去看妇科医生进行乳房和盆腔检查，并讨论她们对使用OCs的担忧。
