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11.5岁时精神病理学的预测因素(0 - 10个月)——哥本哈根儿童队列CCC 2000的一项总人口研究

Predictors (0-10 months) of psychopathology at age 11/2 years - a general population study in The Copenhagen Child Cohort CCC 2000.

作者信息

Skovgaard A M, Olsen E M, Christiansen E, Houmann T, Landorph S L, Jørgensen T

机构信息

Child and Adolescent Psychiatric Centre, University Hospital of Copenhagen, Glostrup, Denmark.

出版信息

J Child Psychol Psychiatry. 2008 May;49(5):553-62. doi: 10.1111/j.1469-7610.2007.01860.x. Epub 2008 Mar 10.

Abstract

BACKGROUND

Epidemiological studies of mental health problems in the first years of life are few. This study aims to investigate infancy predictors of psychopathology in the second year of life.

METHODS

A random general population sample of 210 children from the Copenhagen Child Birth Cohort CCC 2000 was investigated by data from National Danish registers and data collected prospectively from birth in a general child health surveillance programme. Mental health outcome at 1(1/2) years was assessed by clinical and standardised measures including the Child Behavior Check List 1(1/2)-5 (CBCL 1(1/2)-5), Infant Toddler Symptom Check List (ITSCL), Checklist for Autism in Toddlers (CHAT), Bayley Scales of Infant Development (BSID II), Mannheim Eltern Interview (MEI), Parent Child Early Relational Assessment (PC ERA) and Parent Infant Relationship Global Assessment Scale (PIR-GAS), and disordered children were diagnosed according to the International Classification of Diseases (ICD-10) and Diagnostic Classification Zero to Three (DC: 0-3).

RESULTS

Deviant language development in the first 10 months of life predicted the child having any disorder at 1(1/2) years, OR 3.3 (1.4-8.0). Neuro-developmental disorders were predicted by deviant neuro-cognitive functioning, OR 6.8 (2.2-21.4), deviant language development, OR 5.9 (1.9-18.7) and impaired social interaction and communication, OR 3.8 (1.3-11.4). Unwanted pregnancy and parents' negative expectations of the child recorded in the first months of the child's life were significant predictors of relationship disturbances at 1(1/2) years.

CONCLUSIONS

Predictors of neuro-developmental disorders and parent-child relationship disturbances can be identified in the first 10 months of life in children from the general population.

摘要

背景

关于生命最初几年心理健康问题的流行病学研究较少。本研究旨在调查生命第二年精神病理学的婴儿期预测因素。

方法

对哥本哈根儿童出生队列CCC 2000中210名儿童的随机普通人群样本进行调查,数据来自丹麦国家登记处以及在一项普通儿童健康监测计划中从出生起前瞻性收集的数据。通过临床和标准化测量评估1.5岁时的心理健康结果,包括儿童行为检查表1.5 - 5(CBCL 1.5 - 5)、婴幼儿症状检查表(ITSCL)、幼儿自闭症检查表(CHAT)、贝利婴儿发展量表(BSID II)、曼海姆父母访谈(MEI)、亲子早期关系评估(PC ERA)和亲子关系全球评估量表(PIR - GAS),并根据国际疾病分类(ICD - 10)和零至三岁诊断分类(DC:0 - 3)对有障碍的儿童进行诊断。

结果

生命前10个月语言发育异常预测儿童在1.5岁时患有任何障碍,比值比为3.3(1.4 - 8.0)。神经发育障碍可由神经认知功能异常预测,比值比为6.8(2.2 - 21.4),语言发育异常,比值比为5.9(1.9 - 18.7),以及社交互动和沟通受损,比值比为3.8(1.3 - 11.4)。意外怀孕以及在孩子出生后最初几个月记录的父母对孩子的负面期望是1.5岁时关系障碍的重要预测因素。

结论

在普通人群儿童生命的前10个月,可以识别出神经发育障碍和亲子关系障碍的预测因素。

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