Skovgaard Anne Mette, Houmann Tine, Christiansen Eva, Landorph Susanne, Jørgensen Torben, Olsen E M, Heering K, Kaas-Nielsen S, Samberg V, Lichtenberg A
Child and Adolescent Psychiatric Centre, University Hospital of Copenhagen, Glostrup, Denmark.
J Child Psychol Psychiatry. 2007 Jan;48(1):62-70. doi: 10.1111/j.1469-7610.2006.01659.x.
The Copenhagen Child Cohort, CCC 2000, was established to investigate developmental psychopathology prospectively from birth in a general population.
A random sample of 211 children from the CCC 2000 was investigated when the children were 1(1/2) years of age. The prevalence and associates of mental health problems and psychopathology were studied by clinical and standardised strategies, including videotape recordings, parent interviews and the following instruments: The Child Behavior Check List 1(1/2)-5 (CBCL 1(1/2)-5), The Infant Toddler Symptom Check List (ITSCL), Checklist for Autism in Toddlers (CHAT), Bayley Scales of Infant Development II (BSID II), The Parent Child Early Relationship Assessment (PC ERA) and Parent Infant Relationship Global Assessment Scale (PIR-GAS).
Mental health problems according to International Classification of Diseases (ICD-10) and Diagnostic Classification Zero to Three (DC 0-3) diagnoses were found in 16-18% of 1(1/2)-year-old children. Most common were disturbances of emotion, behaviour and eating and the DC 0-3 diagnosis of regulatory disorder. Parent-child relationship disturbances were found in 8%. High psychosocial risk was significantly associated with emotional and behavioural disorders (OR 3.1 95% (1.2-8.1)) and disturbed parent-child relationship (OR 5.0 95% (1.6-16.0)). The strongest association of risk was found between relationship disorders and emotional and behavioural disorders (OR 11.6 95% (3.8-37.5)).
The prevalence and distribution of psychopathology in 1(1/2)-year-old children seem to correspond to the distributions among older children. Disturbances in parent-child relationship have a key position in the risk mechanisms in early child psychopathology.
哥本哈根儿童队列研究（CCC 2000）旨在对普通人群中从出生起的发育性精神病理学进行前瞻性研究。
从CCC 2000中随机抽取211名儿童，在他们1.5岁时进行调查。通过临床和标准化策略研究心理健康问题和精神病理学的患病率及相关因素，包括录像记录、家长访谈以及以下工具：儿童行为检查表1.5 - 5岁版（CBCL 1.5 - 5）、婴幼儿症状检查表（ITSCL）、幼儿自闭症检查表（CHAT）、贝利婴幼儿发展量表第二版（BSID II）、亲子早期关系评估量表（PC ERA）和亲子关系整体评估量表（PIR - GAS）。
根据国际疾病分类（ICD - 10）和诊断分类零至三岁版（DC 0 - 3）诊断，1.5岁儿童中16% - 18%存在心理健康问题。最常见的是情绪、行为和饮食障碍以及DC 0 - 3诊断的调节障碍。8%的儿童存在亲子关系障碍。高心理社会风险与情绪和行为障碍（比值比3.1，95%置信区间（1.2 - 8.1））以及亲子关系障碍（比值比5.0，95%置信区间（1.6 - 16.0））显著相关。风险与关系障碍和情绪及行为障碍之间的关联最强（比值比11.6，95%置信区间（3.8 - 37.5））。
1.5岁儿童精神病理学的患病率和分布似乎与大龄儿童的分布情况相符。亲子关系障碍在儿童早期精神病理学风险机制中具有关键地位。
