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CD45: a leukocyte-specific member of the protein tyrosine phosphatase family.

作者信息

Trowbridge I S, Ostergaard H L, Johnson P

机构信息

Department of Cancer Biology, Salk Institute, San Diego, CA 92186-5800.

出版信息

Biochim Biophys Acta. 1991 Oct 16;1095(1):46-56. doi: 10.1016/0167-4889(91)90043-w.

DOI:10.1016/0167-4889(91)90043-w
PMID:1834176
Abstract
摘要

相似文献

1
CD45: a leukocyte-specific member of the protein tyrosine phosphatase family.CD45：蛋白酪氨酸磷酸酶家族的一种白细胞特异性成员。
Biochim Biophys Acta. 1991 Oct 16;1095(1):46-56. doi: 10.1016/0167-4889(91)90043-w.
2
Tyrosine phosphorylation of CD45 phosphotyrosine phosphatase by p50csk kinase creates a binding site for p56lck tyrosine kinase and activates the phosphatase.p50csk激酶对CD45磷酸酪氨酸磷酸酶进行酪氨酸磷酸化，为p56lck酪氨酸激酶创造一个结合位点并激活该磷酸酶。
Mol Cell Biol. 1994 Feb;14(2):1308-21. doi: 10.1128/mcb.14.2.1308-1321.1994.
3
Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor.蛋白酪氨酸磷酸酶CD45对Src家族成员的调控与通过T细胞受体的跨膜信号传导之间的相关性。
Proc Natl Acad Sci U S A. 1993 Feb 15;90(4):1402-6. doi: 10.1073/pnas.90.4.1402.
4
Regulation and structure-function relationship of CD45.CD45的调控及其结构与功能的关系
Biochem Soc Trans. 1992 Feb;20(1):174-8. doi: 10.1042/bst0200174.
5
CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck.CD45 特异性调节 Lck 与包含 Lck 负调节酪氨酸的磷酸肽的结合。
EMBO J. 1993 Jan;12(1):315-21. doi: 10.1002/j.1460-2075.1993.tb05659.x.
6
Interaction of CD4:lck with the T cell receptor/CD3 complex induces early signaling events in the absence of CD45 tyrosine phosphatase.在缺乏CD45酪氨酸磷酸酶的情况下，CD4:lck与T细胞受体/CD3复合物的相互作用会诱导早期信号事件。
Eur J Immunol. 1992 Mar;22(3):661-8. doi: 10.1002/eji.1830220308.
7
A functional complex is formed in human T lymphocytes between the protein tyrosine phosphatase CD45, the protein tyrosine kinase p56lck and pp32, a possible common substrate.在人类T淋巴细胞中，蛋白酪氨酸磷酸酶CD45、蛋白酪氨酸激酶p56lck和一种可能的共同底物pp32之间形成了一个功能复合体。
Eur J Immunol. 1991 Oct;21(10):2469-77. doi: 10.1002/eji.1830211025.
8
CD45 and RPTPalpha display different protein tyrosine phosphatase activities in T lymphocytes.CD45和RPTPα在T淋巴细胞中表现出不同的蛋白酪氨酸磷酸酶活性。
Biochem J. 1997 Nov 1;327 ( Pt 3)(Pt 3):867-76. doi: 10.1042/bj3270867.
9
The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation.TCR信号传导和调节需要CD45膜近端磷酸酶结构域的催化活性。
EMBO J. 1994 Sep 1;13(17):4002-10. doi: 10.1002/j.1460-2075.1994.tb06716.x.
10
The role of p56lck and p59fyn tyrosine kinases and CD45 protein tyrosine phosphatase in T-cell development and clonal selection.p56lck和p59fyn酪氨酸激酶以及CD45蛋白酪氨酸磷酸酶在T细胞发育和克隆选择中的作用。
Immunol Rev. 1993 Oct;135:183-214. doi: 10.1111/j.1600-065x.1993.tb00649.x.

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黑色素瘤缺失基因2在脊髓损伤中的表达及定位
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Generation of a monoclonal antibody recognizing the heavily glycosylated CD45 protein and its application on identifying circulating tumor cells.一种识别高度糖基化CD45蛋白的单克隆抗体的产生及其在鉴定循环肿瘤细胞中的应用。
PLoS One. 2018 Feb 9;13(2):e0192506. doi: 10.1371/journal.pone.0192506. eCollection 2018.
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Hyperoxia-Induced Proliferative Retinopathy: Early Interruption of Retinal Vascular Development with Severe and Irreversible Neurovascular Disruption.高氧诱导性增殖性视网膜病变：视网膜血管发育早期中断伴严重且不可逆的神经血管破坏
PLoS One. 2016 Nov 18;11(11):e0166886. doi: 10.1371/journal.pone.0166886. eCollection 2016.
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Molecular subsets in the gene expression signatures of scleroderma skin.硬皮病皮肤基因表达特征中的分子亚群。
PLoS One. 2008 Jul 16;3(7):e2696. doi: 10.1371/journal.pone.0002696.
8
CD45 enhances positive selection and is expressed at a high level in large, cycling, positively selected CD4+CD8+ thymocytes.CD45增强阳性选择，并在大型、处于细胞周期、经阳性选择的CD4⁺CD8⁺胸腺细胞中高水平表达。
Immunology. 1997 May;91(1):95-103. doi: 10.1046/j.1365-2567.1997.00216.x.
9
The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation.CD45的胞外结构域控制与CD4-T细胞受体复合物的结合以及对抗原特异性刺激的反应。
J Exp Med. 1996 Jan 1;183(1):249-59. doi: 10.1084/jem.183.1.249.
10
CD45 expression by murine B cells and T cells: alteration of CD45 isoforms in subpopulations of activated B cells.小鼠B细胞和T细胞的CD45表达：活化B细胞亚群中CD45异构体的改变。
Immunol Res. 1993;12(1):21-36. doi: 10.1007/BF02918366.