Harrison L, Dastidar P, Eskola H, Järvenpää R, Pertovaara H, Luukkaala T, Kellokumpu-Lehtinen P-L, Soimakallio S
Tampere University Medical School, Tampere, Finland; Tampere University of Technology, Tampere, Finland.
Comput Biol Med. 2008 Apr;38(4):519-24. doi: 10.1016/j.compbiomed.2008.01.016. Epub 2008 Mar 14.
The aim here is to show that texture parameters of magnetic resonance imaging (MRI) data changes in lymphoma tissue during chemotherapy. Ten patients having non-Hodgkin lymphoma masses in the abdomen were imaged for chemotherapy response evaluation three consecutive times. The analysis was performed with MaZda texture analysis (TA) application. The best discrimination in lymphoma MRI texture was obtained within T2-weighted images between the pre-treatment and the second response evaluation stage. TA proved to be a promising quantitative means of representing lymphoma tissue changes during medication follow-up.
本文旨在表明化疗期间淋巴瘤组织中磁共振成像（MRI）数据的纹理参数会发生变化。对10例腹部患有非霍奇金淋巴瘤肿块的患者进行了连续三次成像，以评估化疗反应。使用MaZda纹理分析（TA）应用程序进行分析。在T2加权图像中，预处理阶段和第二次反应评估阶段之间在淋巴瘤MRI纹理方面获得了最佳区分。TA被证明是一种在药物随访期间表征淋巴瘤组织变化的有前景的定量方法。
