Foulongne V, Segondy M
Unité de virologie, pôle d'infectiologie, CHU de Montpellier-St-Eloi, 80, avenue A.-Fliche, 34295 Montpellier cedex 5, France.
Pathol Biol (Paris). 2009 Mar;57(2):197-202. doi: 10.1016/j.patbio.2008.01.001. Epub 2008 Mar 17.
The human bocavirus (HBoV) has been recently identified by means of molecular screening techniques in respiratory tract secretions from children with acute respiratory tract disease. This virus, which belongs to the Parvoviridae family, has been detected worldwide with a 5 to 10% prevalence among children with upper or lower respiratory tract infections, essentially during the winter period. A seroepidemiological study has shown that almost all the children have antibodies to HBoV by the age of five years, and HBoV infection seems to be rare in adults. HBoV is often detected in association with other respiratory viruses. This virus has also been detected in stools, but its role in gastroenteritis has not been yet established. Virological diagnostic of HBoV infection is based on the detection of viral DNA by PCR. Viral load determination by viral DNA quantitation in respiratory tract secretions could be a tool to differentiate between symptomatic HBoV infection and virus carriage.
人博卡病毒（HBoV）最近通过分子筛查技术在患有急性呼吸道疾病儿童的呼吸道分泌物中被发现。这种病毒属于细小病毒科，在全球范围内均有检测到，在患有上呼吸道或下呼吸道感染的儿童中患病率为5%至10%，主要发生在冬季。一项血清流行病学研究表明，几乎所有儿童在五岁时都有抗HBoV抗体，HBoV感染在成年人中似乎很少见。HBoV经常与其他呼吸道病毒一起被检测到。这种病毒也在粪便中被检测到，但其在肠胃炎中的作用尚未确定。HBoV感染的病毒学诊断基于通过PCR检测病毒DNA。通过对呼吸道分泌物中的病毒DNA进行定量来确定病毒载量，可能是区分有症状的HBoV感染和病毒携带的一种工具。
