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[原发性甲状旁腺功能亢进症与多发性骨髓瘤并存:关联及罕见表现]

[Coexistence of primary hyperparathyroidism and multiple myeloma: association and rare manifestations].

作者信息

Bogas Mónica, Costa Lúcia, Araújo Domingos

机构信息

Serviço de Reumatologia, Centro Hospitalar do Alto Minho, Ponte de Lima, Portugal.

出版信息

Acta Reumatol Port. 2008 Jan-Mar;33(1):98-105.

Abstract

Diseases such as multiple myeloma and primary hyperparathyroidism are occasionally found in the elderly. Although very rare, the coexistence of both in the same patient has been described in the literature. The coincidence of manifestations of both diseases, namely hypercalcemia and osteopenia, may difficult the diagnosis, turning it into a challenge. The authors report a case of a female patient in whom the investigation of hypercalcemia and musculoskeletal manifestations led to a simultaneous diagnosis of multiple myeloma and primary hyperparathyroidism. With this case, they also emphasise clinical and radiological manifestations of these diseases, nowadays rarely observed, and related to the long time clinical evolution.

摘要

多发性骨髓瘤和原发性甲状旁腺功能亢进等疾病在老年人中偶尔可见。虽然极为罕见,但同一患者同时患有这两种疾病的情况在文献中已有记载。这两种疾病表现的重合,即高钙血症和骨质减少,可能会使诊断变得困难,成为一项挑战。作者报告了一例女性患者,对其高钙血症和肌肉骨骼表现进行检查后,同时诊断出多发性骨髓瘤和原发性甲状旁腺功能亢进。通过该病例,作者还强调了这些疾病如今很少见的临床和放射学表现,以及与长期临床病程的相关性。

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