• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

硫喷妥钠和舒芬太尼对5-羟色胺诱导的无内皮犬冠状动脉环收缩的影响。

Effects of sodium pentothal and sufentanil on serotonin induced constriction of canine coronary artery rings without endothelium.

作者信息

Introna R P, Pruett J K, Martin D C, Josephson D, Manabe M

机构信息

Department of Anesthesiology, Medical College of Georgia, Augusta 30912.

出版信息

Gen Pharmacol. 1991;22(4):589-94. doi: 10.1016/0306-3623(91)90061-a.

DOI:10.1016/0306-3623(91)90061-a
PMID:1834517
Abstract
  1. The individual and combined effects of sufentanil and sodium pentothal on canine coronary artery vasomotor responses to 5-HT were studied in an isolated vascular ring preparation. 2. Clinical concentrations of sufentanil have little effect on basal coronary tension or constriction induced by either 5-HT or sodium pentothal individually, until very high doses greater than 0.26 microM are reached. 3. Sodium pentothal causes coronary constriction at clinical concentrations and this effect is additive and possibly potentiated when combined with 5-HT. 4. Sufentanil inhibits coronary constriction induced by the combination of sodium pentothal and 5-HT.
摘要
  1. 在离体血管环标本中研究了舒芬太尼和硫喷妥钠对犬冠状动脉血管运动反应至5-羟色胺（5-HT）的个体及联合效应。2. 舒芬太尼的临床浓度对基础冠状动脉张力或由5-HT或硫喷妥钠单独诱导的收缩作用很小，直到达到大于0.26微摩尔/升的非常高剂量。3. 硫喷妥钠在临床浓度时引起冠状动脉收缩，并且当与5-HT联合时这种效应是相加的且可能增强。4. 舒芬太尼抑制由硫喷妥钠和5-HT联合诱导的冠状动脉收缩。

相似文献

1
Effects of sodium pentothal and sufentanil on serotonin induced constriction of canine coronary artery rings without endothelium.硫喷妥钠和舒芬太尼对5-羟色胺诱导的无内皮犬冠状动脉环收缩的影响。
Gen Pharmacol. 1991;22(4):589-94. doi: 10.1016/0306-3623(91)90061-a.
2
Leukocyte and platelet-derived factors augment canine coronary constriction to serotonin.
Am J Physiol. 1990 Oct;259(4 Pt 2):H1161-70. doi: 10.1152/ajpheart.1990.259.4.H1161.
3
Study on the effects of six intravenous anesthetic agents on regional ventricular function in dogs (thiopental, etomidate, propofol, fentanyl, sufentanil, alfentanil).六种静脉麻醉剂对犬局部心室功能的影响研究（硫喷妥钠、依托咪酯、丙泊酚、芬太尼、舒芬太尼、阿芬太尼）。
Acta Anaesthesiol Belg. 1991;42(1):3-39.
4
Effects of opioids on vasoresponsiveness of porcine coronary artery.阿片类药物对猪冠状动脉血管反应性的影响。
Anesth Analg. 1992 Jun;74(6):889-96. doi: 10.1213/00000539-199206000-00019.
5
Direct effects of fentanyl on canine coronary artery rings.芬太尼对犬冠状动脉环的直接作用。
Life Sci. 1995 Mar 3;56(15):1265-73. doi: 10.1016/0024-3205(95)00072-0.
6
Effects of U46619 on contractions to 5-HT, sumatriptan and methysergide in canine coronary artery and saphenous vein in vitro.U46619对犬冠状动脉和隐静脉体外5-羟色胺、舒马曲坦和甲基麦角新碱收缩作用的影响。
Br J Pharmacol. 1995 Oct;116(4):2183-90. doi: 10.1111/j.1476-5381.1995.tb15052.x.
7
Adenosine inhibits leukocyte-induced vasoconstriction.腺苷可抑制白细胞诱导的血管收缩。
Am J Physiol. 1996 Dec;271(6 Pt 2):H2622-8. doi: 10.1152/ajpheart.1996.271.6.H2622.
8
Induction of anesthesia with small doses of sufentanil or fentanyl: dose versus EEG response, speed of onset, and thiopental requirement.小剂量舒芬太尼或芬太尼诱导麻醉：剂量与脑电图反应、起效速度及硫喷妥钠需求量的关系
Anesthesiology. 1989 Jan;70(1):26-30. doi: 10.1097/00000542-198901000-00007.
9
Propofol and thiopental attenuate the contractile response to vasoconstrictors in human and porcine coronary artery segments.丙泊酚和硫喷妥钠可减弱人及猪冠状动脉节段对血管收缩剂的收缩反应。
Eur J Anaesthesiol. 2000 Aug;17(8):485-90. doi: 10.1046/j.1365-2346.2000.00713.x.
10
Importance of magnesium and potassium concentration on basal tone and 5-HT-induced contractions in canine isolated coronary artery.镁和钾浓度对犬离体冠状动脉基础张力和5-羟色胺诱导收缩的重要性。
Br J Pharmacol. 1988 Jun;94(2):325-34. doi: 10.1111/j.1476-5381.1988.tb11534.x.