Kojima M
Acta Pathol Jpn. 1976 May;26(3):273-94. doi: 10.1111/j.1440-1827.1976.tb00880.x.
From the author's hitherto studies on the reticuloendothelial system (RES) it was concluded that the RES is not a single cell system of identical origin, morphology and function but is a group of several types of cells of different origin. From this point of view the heterogeneity of tumors of the RES was studied to reveal the following results. Tumors of the "Reticuloendothel" (Aschoff) reveal pictures of endothelioma, while tumors of histiocytes in connective tissue show findings of fibrohistiocytoma. Histiocytes and reticulum cells of lymph nodes are respectively independent cells, and reticulum cells do not partake in the in the development of histiocytosis or histiocytic sarcoma. Follicular lymphoma is a neoplastic growth of reticulum cells having desmosomes in lymph follicles, and tumor cells of the majority of reticulum cell sarcoma are similar to the cells forming the lymph node anlage in the early fetal stage (lymphoreticular cell). Ewing's sarcoma is considered to be a kind of angiopericytoma.
根据作者此前对网状内皮系统（RES）的研究得出结论，RES并非起源、形态和功能相同的单一细胞系统，而是由几种不同起源的细胞组成的群体。从这一观点出发，对RES肿瘤的异质性进行了研究，得出以下结果。“网状内皮”（阿绍夫）肿瘤呈现内皮瘤的表现，而结缔组织中组织细胞的肿瘤则显示纤维组织细胞瘤的特征。淋巴结的组织细胞和网状细胞分别是独立的细胞，网状细胞不参与组织细胞增多症或组织细胞肉瘤的发生发展。滤泡性淋巴瘤是淋巴滤泡中具有桥粒的网状细胞的肿瘤性生长，大多数网状细胞肉瘤的肿瘤细胞类似于胎儿早期形成淋巴结原基的细胞（淋巴网状细胞）。尤因肉瘤被认为是一种血管外皮细胞瘤。
