Vásquez Luz M, Pavlin Charles J, McGowan Hugh, Yücel Yeni, Simpson E Rand
Department of Ocular Oncology, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada.
Can J Ophthalmol. 2008 Apr;43(2):229-33. doi: 10.1139/i08-025.
Diagnosis of ring melanoma is clinically difficult since the mass can remain hidden with standard slit-lamp biomicroscopy. The aim of this study was to evaluate the utility of ultrasound biomicroscopy (UBM) as a diagnostic tool for ring melanoma of the ciliary body.
This was a retrospective study of 6 eyes of 6 patients at Princess Margaret Hospital, Toronto, Ont., with a diagnosis of ring melanoma of the ciliary body. The tumor extension was measured clinically, gonioscopically, ultrasonographically (by UBM), and pathologically.
Since 2000, 6 cases of ring melanoma have been diagnosed at Princess Margaret Hospital: 2 women and 4 men, median age 57 years. Five patients presented as uncontrolled hyperchromic glaucoma (83%). Ciliary body involvement on slit-lamp examination ranged from 60 to 180 degrees. Ciliary body involvement as assessed by UBM ranged from 180 to 300 degrees. Tumor extension according to pathological examination ranged from 210 to 360 degrees. With these measures, the ring melanoma clinical criteria were not filled by 5 patients.
UBM is an important tool in determining the extent of ciliary body involvement and classifying these lesions.
环状黑色素瘤的诊断在临床上具有挑战性,因为在标准裂隙灯生物显微镜检查下肿块可能难以发现。本研究的目的是评估超声生物显微镜(UBM)作为睫状体环状黑色素瘤诊断工具的效用。
这是一项对安大略省多伦多玛格丽特公主医院6例诊断为睫状体环状黑色素瘤患者的6只眼睛进行的回顾性研究。通过临床、前房角镜、超声(UBM)及病理检查测量肿瘤的范围。
自2000年以来,玛格丽特公主医院共诊断出6例环状黑色素瘤:2例女性,4例男性,中位年龄57岁。5例患者表现为难以控制的色素性青光眼(83%)。裂隙灯检查显示睫状体受累范围为60至180度。UBM评估的睫状体受累范围为180至300度。病理检查显示肿瘤范围为210至360度。根据这些测量结果,5例患者不符合环状黑色素瘤的临床诊断标准。
UBM是确定睫状体受累范围和对这些病变进行分类的重要工具。