Grajek S, Lesiak M, Pyda M, Paradowski S, Zajac M
I Kliniki Kardiologii Instytutu Kardiologii Akademii Medycznej im. K. Marcinkowskiego, Poznaniu.
Kardiol Pol. 1991;34(6):357-62.
Morphometric evaluation of the epicardial arteries is described in detail in 103 patients with various forms of cardiac hypertrophy. Coronary lumen diameter increases with aging regardless of the cardiac mass. Such an increase is observed in some particular types of cardiac hypertrophy and presumably is caused by the changes of intramuscular vessels and diminished perfusion. In patients with so called myocardial atherosclerosis correlation between coronary lumen diameter age and cardiac mass is opposite. In some forms of cardiac hypertrophy the increment of coronary lumen diameter is accompanied by the increase of the cross sectional area of the artery. In this pattern the increase of lumen diameter is not due to passive vessel dilatation because significant thickening of its wall can be seen. Age appeared to be the most important factor influencing the coronary lumen diameter within the whole population, although this correlation can hardly be seen in patients with "myocardial arteriosclerosis".
对103例各种形式心脏肥大患者的心外膜动脉进行了详细的形态计量学评估。无论心脏重量如何，冠状动脉管腔直径都会随年龄增长而增加。在某些特定类型的心脏肥大中也观察到这种增加，推测是由肌内血管变化和灌注减少引起的。在所谓的心肌动脉粥样硬化患者中，冠状动脉管腔直径、年龄与心脏重量之间的相关性相反。在某些形式的心脏肥大中，冠状动脉管腔直径的增加伴随着动脉横截面积的增加。在这种模式下，管腔直径的增加并非由于血管被动扩张，因为可以看到其壁显著增厚。年龄似乎是影响整个人群冠状动脉管腔直径的最重要因素，尽管在“心肌动脉硬化”患者中几乎看不到这种相关性。
