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伊里扎洛夫与单轨固定器治疗长骨骨不连的疗效分析:一项系统评价与比例Meta分析

Outcome analysis of ilizarov and monorail fixators in the treatment of nonunion of long bones: A systematic review and proportion meta-analysis.

作者信息

Maheshwari Vikas, Raja Balgovind S, Bahadur Bom, Regmi Anil, Dhingra Mohit, Gowda Aditya K S

机构信息

Department of Orthopeaedics, All India Institute of Medical Sciences, Rishikesh, India.

Department of Orthopaedics, All India Institute of Medical Sciences, Patna, India.

出版信息

J Clin Orthop Trauma. 2023 May 18;40:102170. doi: 10.1016/j.jcot.2023.102170. eCollection 2023 May.

Abstract

INTRODUCTION

Nonunion of long bones is a major complication following fractures that requires a substantial amount of investment both monetary and time from patients and surgeons. The need to comprehensively understand the complications, outcomes and distraction capability is profound, which necessitates a review of current evidence on special fixators used for distraction. The current systematic review aims to study the available literature on distraction osteogenesis using special fixators (Ilizarov and Limb Reconstruction System) in the management of nonunion (infected and non-infected).

METHODS

Cochrane Library, PubMed, Scopus were searched until January 2022. The review included all original studies which used Ilizarov or Monorail Fixators/LRS in the treatment of nonunion of long bones. The quality of studies was assessed using the Modified Coleman Methodology Score.

RESULTS

A total of 35 original studies with Ilizarov (n = 29) and LRS (n = 8) were selected including two comparative studies. The pooled data meta-analysis and the subgroup analysis of these studies found both Ilizarov and LRS fixator yield similar functional outcomes for the treatment of long bones nonunion.

CONCLUSION

The review was conducted to understand the scenario of nonunion in long bones. Pin tract infection is found to be the most common complication followed by adjacent joint stiffness and deformity. In our review we observed that both external fixator time and index were lower in LRS compared to Ilizarov group. Further RCT are required comparing Ilizarov and LRS fixators to effectively comment upon the superiority of the implants.

摘要

引言

长骨不愈合是骨折后的一种主要并发症,患者和外科医生在金钱和时间上都需要大量投入。全面了解并发症、治疗结果和牵张能力的需求非常迫切,这就需要对用于牵张的特殊固定器的现有证据进行综述。本系统评价旨在研究关于使用特殊固定器(伊里扎洛夫固定器和肢体重建系统)进行牵张成骨治疗不愈合(感染性和非感染性)的现有文献。

方法

检索Cochrane图书馆、PubMed、Scopus直至2022年1月。该综述纳入了所有使用伊里扎洛夫固定器或单轨固定器/肢体重建系统治疗长骨不愈合的原始研究。采用改良科尔曼方法评分评估研究质量。

结果

共纳入35项原始研究,其中使用伊里扎洛夫固定器的有29项,使用肢体重建系统的有8项,包括两项比较研究。对这些研究进行的汇总数据荟萃分析和亚组分析发现,伊里扎洛夫固定器和肢体重建系统在治疗长骨不愈合方面产生的功能结果相似。

结论

本综述旨在了解长骨不愈合的情况。发现针道感染是最常见的并发症,其次是相邻关节僵硬和畸形。在我们的综述中,我们观察到与伊里扎洛夫组相比,肢体重建系统的外固定时间和指数更低。需要进一步进行随机对照试验来比较伊里扎洛夫固定器和肢体重建系统,以有效评价植入物的优越性。

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