早产儿对乙型肝炎疫苗的免疫反应。
Immune response to hepatitis B vaccine in premature neonates.
作者信息
Chawareewong S, Jirapongsa A, Lokaphadhana K
机构信息
Department of Pediatrics, Bangkok Christian Hospital, Thailand.
出版信息
Southeast Asian J Trop Med Public Health. 1991 Mar;22(1):39-40.
The immunogenecity of a recombinant yeast-derived hepatitis B vaccine in 25 premature infants who were born to HBsAg negative mothers was studied. The gestational ages were 28-37 weeks and birth weights were 1300-2000 grams. Seroconversion occurred in 22 infants, the anti HBs titers varied between 50 and 13,470 IU/L (Geometric mean titer = 542 IU/L). Seroconversion rate = 88%. The response did not vary with gestational age, birth weight or illness status.
对25名母亲乙肝表面抗原（HBsAg）阴性的早产儿接种重组酵母乙型肝炎疫苗后的免疫原性进行了研究。这些早产儿的胎龄为28 - 37周，出生体重为1300 - 2000克。22名婴儿出现血清学转换，抗HBs滴度在50至13470 IU/L之间（几何平均滴度 = 542 IU/L）。血清学转换率 = 88%。应答情况不受胎龄、出生体重或疾病状态的影响。
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