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[实验性糖尿病中椎前神经节的超微结构研究]

[Ultrastructural study of the prevertebral ganglia in experimental diabetes].

作者信息

Morte García L, Ramón y Cajal Junquera S, Cuervas-Mons Finat M

机构信息

Departamento de Anatomía Patológica. Colegio Universitario de Soria.

出版信息

Actas Luso Esp Neurol Psiquiatr Cienc Afines. 1991 May-Jun;19(3):167-73.

PMID:1835252
Abstract

Prevertebral ganglia of rats with streptozotocin-induced diabetes have been studied by electron microscope, in different periods of evolution of the illness. The cytoplasm of the ganglion cells showed dense deposits of neurofilaments and several degenerative changes as vacuolization and accumulation of residual bodies. The unmyelinated axons were markedly swollen showing degenerative and dystrophic changes which increased with the duration of the diabetes. Control animals of the same age did not show this type of changes.

摘要

利用电子显微镜对链脲佐菌素诱导糖尿病大鼠的椎前神经节在疾病发展的不同阶段进行了研究。神经节细胞的细胞质显示出神经丝的致密沉积以及一些退行性变化,如空泡化和残余小体的积累。无髓轴突明显肿胀,呈现退行性和营养不良性变化,且随着糖尿病病程的延长而加重。相同年龄的对照动物未出现此类变化。

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