Karimian-Teherani Daniela, Kinaciyan Tamar, Tanew Adrian
Division of General Dermatology, Medical University of Vienna, Vienna, Austria.
Photodermatol Photoimmunol Photomed. 2008 Apr;24(2):99-101. doi: 10.1111/j.1600-0781.2008.00346.x.
Heracleum plants occur in numerous species worldwide and may cause phototoxic reactions due to its content of various furocoumarins. In this case report, a widespread photoallergic contact dermatitis after exposure to Heracleum giganteum (giant bear claw) is described. A photopatch test with extracts from the stem, leaves and seeds of the giant bear claw revealed a positive papulovesicular reaction that already appeared at 24 h and peaked at 72 h after irradiation with 5 J/cm(2) UVA. The unirradiated controls remained negative. We conclude that in rare cases Heracleum plants may cause severe photoallergic reactions that can be verified by photopatch testing.
独活属植物在全球有众多物种，因其含有多种呋喃香豆素可能会引起光毒性反应。在本病例报告中，描述了一例接触巨型独活（巨熊爪）后发生的广泛光变应性接触性皮炎。对巨熊爪的茎、叶和种子提取物进行光斑贴试验，结果显示在以5 J/cm²紫外线A照射后24小时出现阳性丘疹水疱反应，并在72小时达到峰值。未照射的对照仍为阴性。我们得出结论，在罕见情况下，独活属植物可能会引起严重的光变应性反应，光斑贴试验可对此进行验证。
