光斑贴试验：一项2004年至2006年的意大利多中心研究。
Photopatch tests: an Italian multicentre study from 2004 to 2006.
作者信息
Pigatto Paolo Daniele, Guzzi Gianpaolo, Schena Donatella, Guarrera Marcella, Foti Caterina, Francalanci Stefano, Cristaudo Antonio, Ayala Fabio, Vincenzi Colombina
机构信息
Department of Technology for Health, IRCCS, Galeazzi Dermatological Clinic, University of Milan, Via Galeazzi 4, 20161 Milan, Italy.
出版信息
Contact Dermatitis. 2008 Aug;59(2):103-8. doi: 10.1111/j.1600-0536.2008.01374.x.
BACKGROUND
Evaluation of possible photoallergic contact dermatitis in at-risk populations is often not undertaken, and an agreed methodology for investigation is uncommonly used.
OBJECTIVES
We conducted a retrospective multicentre study to determine the prevalence of photoallergic contact dermatitis in Italy.
METHODS
A total of 1082 patients with histories and clinical features suggestive of photoallergic contact dermatitis were evaluated. All the patients had undergone photopatch testing with allergens proposed for Italy as well as other substances suggested by each patient's personal history.
RESULTS
234 patients (21.6%) were positive to at least one test substance of the standard photopatch testing series or to added substances. 234 patients (21.6%) were positive to at least one substance with a total of 290 reactions. 204 of the reactions were typically photoallergic; 68 reactions were allergic and within this group 10 were photoaugmented reactions; 18 reactions were considered to be phototoxic.
CONCLUSION
The predominant group of photoallergens was drugs, followed by organic UV filters and antimicrobial agents.
背景
对高危人群中可能的光变应性接触性皮炎的评估通常未进行，且很少使用公认的调查方法。
目的
我们进行了一项回顾性多中心研究，以确定意大利光变应性接触性皮炎的患病率。
方法
共评估了1082例有光变应性接触性皮炎病史和临床特征的患者。所有患者均接受了针对意大利建议的变应原以及每位患者个人病史所提示的其他物质的光斑贴试验。
结果
234例患者（21.6%）对标准光斑贴试验系列中的至少一种试验物质或添加物质呈阳性反应。234例患者（21.6%）对至少一种物质呈阳性反应，共有290次反应。其中204次反应为典型的光变应性反应；68次反应为变应性反应，其中10次为光增强反应；18次反应被认为是光毒性反应。
结论
主要的光变应原组为药物，其次是有机紫外线滤过剂和抗菌剂。
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