Ou Yang-Tao, Li Jin-Feng, Fan Zhao-Qing, Fan Tie, Wang Tian-Feng, Xie Yun-Tao, Lin Ben-Yao
Breast Cancer Prevention and Treatment Center, Beijing Cancer Hospital, School of Oncology, Peking University, Beijing 100036, China.
Zhonghua Yi Xue Za Zhi. 2008 Jan 8;88(2):82-4.
To evaluate the utility of ultrasound (US)-guided needle biopsy of ultrasonographic abnormal axillary lymph nodes in the patients with breast cancer.
The pathological results of US-guided needle biopsy and clinical data of 395 primary breast cancer patients with ultrasonographic abnormal axillary nodes, all female, aged 24 - 83, were analyzed retrospectively.
Node metastasis were detected in 277 (70.1%) cases by mean of ultrasound-guided needle biopsy. Among 136 patients with clinical N(0) breast cancer, 65 (47.8%) were proved node positive. Sixty-two patients were diagnosed as pathologically negative by needle biopsy and underwent sentinel lymph node biopsy or axillary lymph node clearance, and pathological examination showed negative axillary lymph node negative. The complete pathological complete remission rate of the metastatic lymph nodes after new adjuvant chemotherapy was 32.3% (62/192).
Ultrasonographic examination of axilla combined with ultrasound-guided needle biopsy of suspicious axillary node is valuable in primary breast cancer treatment.
评估超声（US）引导下对乳腺癌患者超声异常腋窝淋巴结进行穿刺活检的效用。
回顾性分析395例原发性乳腺癌且超声腋窝淋巴结异常患者（均为女性，年龄24 - 83岁）的超声引导下穿刺活检病理结果及临床资料。
通过超声引导下穿刺活检，277例（70.1%）检测到淋巴结转移。在136例临床N(0)期乳腺癌患者中，65例（47.8%）被证实淋巴结阳性。62例经穿刺活检病理诊断为阴性的患者接受了前哨淋巴结活检或腋窝淋巴结清扫，病理检查显示腋窝淋巴结阴性。新辅助化疗后转移淋巴结的完全病理缓解率为32.3%（62/192）。
腋窝超声检查联合超声引导下对可疑腋窝淋巴结进行穿刺活检在原发性乳腺癌治疗中具有重要价值。
