ElSawy K M, Taormina A, Twarock R, Vaughan L
Department of Mathematics, University of York, York YO10 5DD, UK.
J Theor Biol. 2008 May 21;252(2):357-69. doi: 10.1016/j.jtbi.2008.02.003. Epub 2008 Feb 13.
The Caspar-Klug classification of viruses whose protein shell, called viral capsid, exhibits icosahedral symmetry, has recently been extended to incorporate viruses whose capsid proteins are exclusively organised in pentamers. The approach, named 'Viral Tiling Theory', is inspired by the theory of quasicrystals, where aperiodic Penrose tilings enjoy 5-fold and 10-fold local symmetries. This paper analyses the extent to which this classification approach informs dynamical properties of the viral capsids, in particular the pattern of Raman active modes of vibrations, which can be observed experimentally.
对于其蛋白质外壳(称为病毒衣壳)呈现二十面体对称性的病毒,卡斯帕 - 克卢格分类法最近已得到扩展,以纳入其衣壳蛋白仅以五聚体形式组织的病毒。这种方法名为“病毒平铺理论”,其灵感来自准晶体理论,其中非周期性的彭罗斯平铺具有五重和十重局部对称性。本文分析了这种分类方法在多大程度上能够揭示病毒衣壳的动力学特性,特别是通过实验可以观察到的拉曼活性振动模式的模式。