Bartels Ronald H M A, van der Linden Yvette M, van der Graaf Winette T A
Radboud University Nijmegen Medical Centre, Department of Neurosurgery, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
CA Cancer J Clin. 2008 Jul-Aug;58(4):245-59. doi: 10.3322/CA.2007.0016. Epub 2008 Mar 19.
Bone metastases, especially to the spine, are frequently encountered during the course of a malignancy. Due to a worldwide increase of cancer incidence and to a longer life expectancy of patients with cancer, a rise in incidence of bone metastases is observed. A brief historical overview is the base of a review of current treatment options. Despite new developments in the surgical and radiotherapeutic fields, as well as in medical oncology, external beam radiotherapy is the cornerstone of the treatment of spinal metastases. In selected cases, surgical treatment is a proven option. Vertebroplasty or kyphoplasty can also be considered. Supportive medical care does not differ from that given for symptomatic lesions to the skeletal system elsewhere in the body. After discussing the treatment options, an algorithm is given.
骨转移，尤其是脊柱转移，在恶性肿瘤病程中经常出现。由于全球癌症发病率上升以及癌症患者预期寿命延长，骨转移的发病率也在增加。简要的历史概述是回顾当前治疗选择的基础。尽管在外科、放射治疗领域以及医学肿瘤学方面有了新进展，但外照射放疗仍是脊柱转移瘤治疗的基石。在特定病例中，手术治疗是一种已被证实的选择。椎体成形术或后凸成形术也可考虑。支持性医疗护理与针对身体其他部位骨骼系统症状性病变的护理并无不同。在讨论了治疗选择后，给出了一个算法。
