Swift Patrick S
Radiation Oncology, Alta Bates Comprehensive Cancer Center, 2001 Dwight Way, Berkeley, CA 94704, USA.
Orthop Clin North Am. 2009 Jan;40(1):133-44, vii. doi: 10.1016/j.ocl.2008.09.001.
Radiotherapeutic management of vertebral metastases varies based on the extent of disease within the spine and systemically, the histology of the tumor, and the life expectancy of the patient. The goals of pain reduction, structural stability of the axial skeleton, and maintenance of local control for the remainder of the patient's life guide the decision to proceed with a short simple course of standard therapy or a more complex approach with stereotactic regimens. The complex and rigorous processes involved in stereotactic radiotherapy for the spine require close cooperation among the radiation oncologist, neurosurgeon, orthopedic surgeon, and medical oncologist, but the clinical results show that the result is an enhanced quality of life for the patient.
椎体转移瘤的放射治疗管理因脊柱内及全身疾病的范围、肿瘤组织学类型以及患者预期寿命的不同而有所差异。减轻疼痛、维持轴向骨骼结构稳定以及在患者剩余生命中保持局部控制等目标,指导着是采用短期标准治疗方案还是采用更复杂的立体定向治疗方案。脊柱立体定向放射治疗所涉及的复杂而严格的过程需要放射肿瘤学家、神经外科医生、骨科医生和医学肿瘤学家密切合作,但临床结果表明,这能提高患者的生活质量。