Sciubba Daniel M, Nguyen Trang, Gokaslan Ziya L
Department of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA.
Orthop Clin North Am. 2009 Jan;40(1):145-54, viii. doi: 10.1016/j.ocl.2008.09.003.
As survival time increases for many cancers, it is likely that the incidence and prevalence of spinal metastases will increase also. Given that most patients first present with solitary lesions in the spine, proper initial diagnosis and management are of paramount importance in minimizing pain, improving neurologic function, and potentially lengthening survival. Although pain control and standard radiation are still used, spinal stereotactic radiosurgery, vertebroplasty and kyphoplasty, and spinal cord decompression and fusion are now consistently used in aggressive management and offer exciting preliminary results.
随着许多癌症患者生存时间的延长,脊柱转移瘤的发病率和患病率可能也会上升。鉴于大多数患者最初表现为脊柱单发病变,恰当的初始诊断和治疗对于减轻疼痛、改善神经功能以及可能延长生存期至关重要。尽管疼痛控制和标准放疗仍在使用,但脊柱立体定向放射外科、椎体成形术和后凸成形术以及脊髓减压和融合术目前已持续应用于积极治疗中,并取得了令人振奋的初步成果。