TG101348, a JAK2-selective antagonist, inhibits primary hematopoietic cells derived from myeloproliferative disorder patients with JAK2V617F, MPLW515K or JAK2 exon 12 mutations as well as mutation negative patients.
作者信息
Lasho T L, Tefferi A, Hood J D, Verstovsek S, Gilliland D G, Pardanani A
出版信息
Leukemia. 2008 Sep;22(9):1790-2. doi: 10.1038/leu.2008.56. Epub 2008 Mar 20.