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A microculture containing TH2 and dendritic cells supports the production of IgA by clones from both primary and IgA memory B cells and by single germinal center B cells from Peyer's patches.

作者信息

Cebra J J, George A, Schrader C E

机构信息

Department of Biology, University of Pennsylvania, Philadelphia.

出版信息

Immunol Res. 1991;10(3-4):389-92. doi: 10.1007/BF02919727.

DOI:10.1007/BF02919727
PMID:1835491
Abstract
摘要

相似文献

1
A microculture containing TH2 and dendritic cells supports the production of IgA by clones from both primary and IgA memory B cells and by single germinal center B cells from Peyer's patches.包含TH2细胞和树突状细胞的微培养体系支持来自初级和IgA记忆B细胞的克隆以及派尔集合淋巴结单个生发中心B细胞产生IgA。
Immunol Res. 1991;10(3-4):389-92. doi: 10.1007/BF02919727.
2
Responses of single germinal-center B cells in T-cell-dependent microculture.在T细胞依赖的微量培养中单个生发中心B细胞的反应。
Proc Natl Acad Sci U S A. 1991 Jan 1;88(1):11-5. doi: 10.1073/pnas.88.1.11.
3
T cell clones that help IgA responses.
Adv Exp Med Biol. 1987;216A:101-17. doi: 10.1007/978-1-4684-5344-7_13.
4
Dendritic cells support production of IgA and other non-IgM isotypes in clonal microculture.树突状细胞在克隆微培养中支持IgA和其他非IgM同种型的产生。
Int Immunol. 1990;2(6):563-70. doi: 10.1093/intimm/2.6.563.
5
Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches.肠道派尔集合淋巴结中Foxp3+ T细胞优先生成滤泡辅助性B细胞。
Science. 2009 Mar 13;323(5920):1488-92. doi: 10.1126/science.1169152.
6
IgA responses in xid mice: oral antigen primes Peyer's patch cells for in vitro immune responses and secretory antibody production.Xid小鼠中的IgA应答:口服抗原使派尔集合淋巴结细胞致敏以产生体外免疫应答和分泌性抗体。
J Immunol. 1983 Dec;131(6):2616-22.
7
Plasticity of Th17 cells in Peyer's patches is responsible for the induction of T cell-dependent IgA responses.派尔集合淋巴结中 Th17 细胞的可塑性是诱导 T 细胞依赖性 IgA 应答的原因。
Nat Immunol. 2013 Apr;14(4):372-9. doi: 10.1038/ni.2552. Epub 2013 Mar 10.
8
Mechanisms regulating IgA class-specific immunoglobulin production in murine gut-associated lymphoid tissues. I. T cells derived from Peyer's patches that switch sIgM B cells to sIgA B cells in vitro.调节小鼠肠道相关淋巴组织中IgA类特异性免疫球蛋白产生的机制。I. 源自派尔集合淋巴结的T细胞,其在体外可使表面IgM B细胞转换为表面IgA B细胞。
J Exp Med. 1983 Feb 1;157(2):433-50. doi: 10.1084/jem.157.2.433.
9
Elevated membrane IgA+ and CD4+ (T helper) populations in murine Peyer's patch and splenic lymphocytes during dietary administration of the trichothecene vomitoxin (deoxynivalenol).在给小鼠喂食单端孢霉烯族呕吐毒素(脱氧雪腐镰刀菌烯醇)期间,其派伊尔氏结和脾淋巴细胞中的膜IgA⁺和CD4⁺(辅助性T)细胞群体增加。
Food Chem Toxicol. 1990 Jun;28(6):409-20. doi: 10.1016/0278-6915(90)90087-4.
10
Isotype specificity of helper T cell clones. Peyer's patch Th cells preferentially collaborate with mature IgA B cells for IgA responses.辅助性T细胞克隆的同种型特异性。派尔集合淋巴结的Th细胞优先与成熟的IgA B细胞协作以产生IgA应答。
J Exp Med. 1984 Mar 1;159(3):798-811. doi: 10.1084/jem.159.3.798.

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Role of cellular effectors in the induction and maintenance of IgA responses leading to protective immunity against enteric bacterial pathogens.细胞效应因子在诱导和维持 IgA 反应中的作用,这些反应导致对肠道细菌病原体的保护性免疫。
Front Immunol. 2024 Sep 11;15:1446072. doi: 10.3389/fimmu.2024.1446072. eCollection 2024.
2
Human IgA-inducing protein from dendritic cells induces IgA production by naive IgD+ B cells.来自树突状细胞的人IgA诱导蛋白可诱导初始IgD+B细胞产生IgA。
J Immunol. 2009 Feb 15;182(4):1854-9. doi: 10.4049/jimmunol.0801973.
3
Intestinal bacteria condition dendritic cells to promote IgA production.

本文引用的文献

1
Sea star factor blocks development of T-dependent antibody secreting clones by preventing lymphokine secretion.海星因子通过阻止淋巴因子分泌来阻断依赖T细胞的抗体分泌克隆的发育。
Cell Immunol. 1994 Jun;156(1):62-76. doi: 10.1006/cimm.1994.1153.
2
Special features of the priming process for a secretory IgA response. B cell priming with cholera toxin.分泌型IgA应答启动过程的特殊特征。用霍乱毒素启动B细胞。
J Exp Med. 1981 Mar 1;153(3):534-44. doi: 10.1084/jem.153.3.534.
3
Functional anatomy of germinal centers.生发中心的功能解剖学
肠道细菌调节树突状细胞以促进IgA的产生。
PLoS One. 2008 Jul 2;3(7):e2588. doi: 10.1371/journal.pone.0002588.
Am J Anat. 1984 Jul;170(3):421-35. doi: 10.1002/aja.1001700315.
4
Accessory cells in murine Peyer's patch. I. Identification and enrichment of a functional dendritic cell.小鼠派尔集合淋巴结中的辅助细胞。I. 功能性树突状细胞的鉴定与富集。
J Exp Med. 1983 May 1;157(5):1646-59. doi: 10.1084/jem.157.5.1646.
5
Germinal center B cells lack homing receptors necessary for normal lymphocyte recirculation.生发中心B细胞缺乏正常淋巴细胞再循环所需的归巢受体。
J Exp Med. 1983 Mar 1;157(3):813-27. doi: 10.1084/jem.157.3.813.
6
Single-cell studies on hapten-specific B cells: response to T-cell-dependent antigens.对半抗原特异性B细胞的单细胞研究:对T细胞依赖性抗原的反应
Proc Natl Acad Sci U S A. 1984 Apr;81(8):2479-83. doi: 10.1073/pnas.81.8.2479.
7
Clustering of dendritic cells, helper T lymphocytes, and histocompatible B cells during primary antibody responses in vitro.体外初次抗体应答过程中树突状细胞、辅助性T淋巴细胞和组织相容性B细胞的聚集
J Exp Med. 1984 Sep 1;160(3):858-76. doi: 10.1084/jem.160.3.858.
8
Relationship between expression of IgA by Peyer's patch cells and functional IgA memory cells.派尔集合淋巴结细胞的IgA表达与功能性IgA记忆细胞之间的关系。
J Exp Med. 1987 Nov 1;166(5):1405-18. doi: 10.1084/jem.166.5.1405.
9
Role of the interleukin 2 receptor in differentiation of a clone of Ly-1+ B cells.白细胞介素2受体在Ly-1+ B细胞克隆分化中的作用。
J Immunol. 1987 May 15;138(10):3308-13.
10
Signalling through sIgA on a novel murine B lymphoma.通过新型小鼠B淋巴瘤上的分泌型免疫球蛋白A(sIgA)进行信号传导。
Mol Immunol. 1989 Jul;26(7):593-9. doi: 10.1016/0161-5890(89)90041-2.