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Hyponatraemia during low-dose carbamazepine therapy.

作者信息

Salawu F, Danburam A

机构信息

Department of Medicine, State Specialist Hospital, Maiduguri 600001, Nigeria.

出版信息

Ann Afr Med. 2007 Dec;6(4):207-8. doi: 10.4103/1596-3519.55693.

DOI:10.4103/1596-3519.55693
PMID:18354950
Abstract

We report the syndrome of inappropriate antidiuresis as a much earlier side-effect of carbamazepine administration in a 29-year Nigerian female patient with generalized tonic-elonic seizures. Although asymptomatic, the biochemical abnormality improved after discontinuation of carbamazepine. Hyponatraemia developed after rechallenge with controlled release carbamazepine. The authors suggest that serum sodium levels be carried out before commencement of carbamazepine and caution be used in prescribing carbamazepine to patients with low or borderline low sodium values.

摘要

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