Malojcic Branko, Mubrin Zdenko, Coric Bojana, Susnic Mirica, Spilich George J
Department of Neurology, University Hospital Centre, Zagreb, Croatia.
J Neurotrauma. 2008 Jan;25(1):30-7. doi: 10.1089/neu.2007.0384.
In this investigation, we explored the impact of mild traumatic brain injury (mTBI) upon short term or working memory and attention. The performance of 37 individuals with mTBI was compared with that of 53 age, sex and education-matched controls. All participants were staff members or individuals seeking medical care at a University hospital serving a large metropolitan area. A battery of computerized tests measured sustained visual attention, short-term memory (STM), simple reaction time, and decision time. Individuals with mTBI showed a performance deficit at sustained visual attention, STM scanning and a trend towards slowing in choice decision making. These observed changes in the cognitive performance of mTBI individuals are hypothesized to be a consequence of impaired central information processing. Our results suggest that mTBI can elicit meaningful cognitive deficits for several months post-injury. Additionally, we believe that the tasks employed in the current investigation demonstrate their utility for understanding cognitive deficits in mTBI individuals.
在本研究中，我们探讨了轻度创伤性脑损伤（mTBI）对短期或工作记忆以及注意力的影响。将37名患有mTBI的个体的表现与53名年龄、性别和教育程度相匹配的对照组个体的表现进行了比较。所有参与者均为在一家服务于大都市地区的大学医院工作的员工或寻求医疗护理的人员。通过一系列计算机化测试来测量持续视觉注意力、短期记忆（STM）、简单反应时间和决策时间。患有mTBI的个体在持续视觉注意力、STM扫描方面表现出缺陷，并且在选择决策方面有变慢的趋势。据推测，mTBI个体认知表现的这些观察到的变化是中枢信息处理受损的结果。我们的结果表明，mTBI在损伤后数月可引发有意义的认知缺陷。此外，我们认为本研究中使用的任务证明了它们在理解mTBI个体认知缺陷方面的效用。
