Carlsson M, Cortes D, Jepsen S, Kanstrup T
Pediatric Intensive Care Unit, Afdeling V, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense C., Denmark.
Arch Dis Child. 2008 Apr;93(4):321-2. doi: 10.1136/adc.2007.123240.
An 18-month-old previous healthy girl who had ingested 442 mg elemental iron/kg was admitted to a paediatric intensive care unit. The child was treated with gastric lavage, whole bowel irrigation and intravenous deferoxamine. After 2 h of standard therapy serum iron had risen threefold to 1362 microg/dl (244 micromol/l). The child was treated with exchange transfusion (ET; 52 ml/kg) and serum iron fell to 134 microg/dl (24 micromol/l). The patient made an uncomplicated recovery. ET should be considered in severe iron poisoning when standard therapy is inadequate.
一名18个月大、此前健康的女童摄入了442毫克元素铁/千克,被收治入儿科重症监护病房。该患儿接受了洗胃、全肠道灌洗及静脉注射去铁胺治疗。标准治疗2小时后,血清铁升高了两倍,达到1362微克/分升(244微摩尔/升)。该患儿接受了换血治疗(52毫升/千克),血清铁降至134微克/分升(24微摩尔/升)。患儿顺利康复。当标准治疗不足时,严重铁中毒应考虑换血治疗。