Talay Fahrettin, Kurt Bahar, Tug Tuncer, Yilmaz Fahrettin, Goksugur Nadir
Department of Chest Diseases, Abant Izzet Baysal University School of Medicine, Bolu, Turkey.
Acta Paediatr. 2008 Apr;97(4):459-62. doi: 10.1111/j.1651-2227.2008.00726.x.
In this study we aimed to detect the prevalence and risk factors of asthma and allergic diseases in children aged between 7 and 14 years old at rural and urban areas of Bolu, Turkey.
Questionnaire of International Study of Asthma and Allergies in Childhood (ISAAC) phase one and questionnaire including questions about family, demographic, socio-economic characteristics of children were applied to 931 schoolchildren who were selected by randomized sampling.
In children, the prevalence of diseases and symptoms were as follows: wheeze ever: 15.5%, asthma: 5.6%, nasal symptoms ever: 41.4%, allergic rhinitis: 23.2%, itchy rash ever: 5.9% and eczema: 5.0%. In multivariate regression analysis, presence of allergic disease in the family was risk factor for wheezing (OR=1.74, 95% CI=1.19-2.76), asthma (OR=2.19, CI=1.06-4.52), allergic rhinitis (OR=2.68, CI=1.80-3.98) and eczema (OR=2.33, CI=1.17-4.65); living in shanties was risk factor for allergic rhinitis (OR=5.26, CI=2.1-13.16); a monthly income below $300 was risk factor for asthma (OR=2.54, CI=1.06-6.08).
It was detected that the prevalence of allergic rhinitis and its symptoms was more common in schoolchildren living in Bolu. Presence of allergic disease in fathers or mothers and low socio-economic level increase the risk of asthma and other allergic diseases in children.
在本研究中,我们旨在检测土耳其博卢城乡地区7至14岁儿童哮喘和过敏性疾病的患病率及危险因素。
采用儿童哮喘和过敏国际研究(ISAAC)第一阶段问卷以及包含儿童家庭、人口统计学、社会经济特征问题的问卷,对通过随机抽样选取的931名学童进行调查。
儿童疾病及症状的患病率如下:曾有喘息:15.5%,哮喘:5.6%,曾有鼻部症状:41.4%,过敏性鼻炎:23.2%,曾有皮疹瘙痒:5.9%,湿疹:5.0%。多因素回归分析显示,家族中有过敏性疾病是喘息(比值比[OR]=1.74,95%可信区间[CI]=1.19 - 2.76)、哮喘(OR=2.19,CI=1.06 - 4.52)、过敏性鼻炎(OR=2.68,CI=1.80 - 3.98)和湿疹(OR=2.33,CI=1.17 - 4.65)的危险因素;居住在棚户区是过敏性鼻炎的危险因素(OR=5.26,CI=2.1 - 13.16);月收入低于300美元是哮喘的危险因素(OR=2.54,CI=1.06 - 6.08)。
研究发现,博卢地区学童中过敏性鼻炎及其症状的患病率更高。父母患有过敏性疾病以及社会经济水平较低会增加儿童患哮喘和其他过敏性疾病的风险。