Naito Toru
Department of General Dentistry, Fukuoka Dental College, Fukuoka, Japan.
Evid Based Dent. 2008;9(1):24. doi: 10.1038/sj.ebd.6400570.
Searches for relevant studies were made using the Cochrane Oral Health Group's Trials Register, CENTRAL, Medline and Embase. The major oral medicine journals were also searched by hand and reference lists of included studies and reviews were checked. Endodontics experts were contacted by e-mail. No language limitations were imposed.
Randomised controlled trials (RCT) and quasi-RCT of root canal treatment were included. Surgical endodontic treatment was excluded. The outcomes considered were the number of teeth extracted for endodontic problems; radiological success (absence of any periapical radiolucency) after at least 1 year; postoperative pain; painkiller use; swelling; or sinus track formation.
Data were collected using a specific extraction form. The validity of the studies included was assessed on the basis of allocation concealment, blindness of the study, and loss of participants. Data were analysed by calculating risk ratios. When valid and relevant data were collected, a meta-analysis of the data was undertaken.
Twelve RCT were included in the review. Four studies had a low risk of bias, four a moderate risk, and another four had a high risk of bias. The frequency of radiological success and immediate postoperative pain were not significantly different between single- and multiple-visit root canal treatments. People who had single-visit treatment reported a higher frequency of painkiller use and swelling, but the results for swelling were not significantly different between the two groups. We found no study that included tooth loss and sinus track formation among its primary outcomes.
No difference exists in the effectiveness of root canal treatment, in terms of radiological success, between single- and multiple-visit treatments. Most short- and long-term complications are also similar in terms of frequency, although patients undergoing a single visit may experience a slightly higher frequency of swelling and are significantly more likely to take painkillers.
通过Cochrane口腔健康小组试验注册库、Cochrane系统评价数据库、医学期刊数据库和Embase检索相关研究。同时也手工检索了主要的口腔医学期刊,并检查了纳入研究和综述的参考文献列表。通过电子邮件联系了牙髓病学专家。未设语言限制。
纳入根管治疗的随机对照试验(RCT)和半随机对照试验。排除外科牙髓治疗。所考虑的结局包括因牙髓问题拔除的牙齿数量;至少1年后的影像学成功(根尖周无任何透射区);术后疼痛;止痛药使用情况;肿胀;或窦道形成。
使用特定的提取表格收集数据。根据分配隐藏、研究的盲法和参与者的失访情况评估纳入研究的有效性。通过计算风险比进行数据分析。当收集到有效且相关的数据时,对数据进行荟萃分析。
该综述纳入了12项RCT。4项研究偏倚风险低,4项中等,另外4项偏倚风险高。单次就诊和多次就诊的根管治疗在影像学成功率和术后即刻疼痛方面无显著差异。接受单次就诊治疗的患者报告止痛药使用和肿胀的频率较高,但两组肿胀结果无显著差异。我们未发现有研究将牙齿脱落和窦道形成作为主要结局。
在影像学成功方面,单次就诊和多次就诊的根管治疗效果无差异。大多数短期和长期并发症的发生率也相似,尽管单次就诊的患者肿胀发生率可能略高,且服用止痛药的可能性显著更高。