Chemistry Department, Faculty of Science, Kuwait University, P.O. Box 5969, Safat 13060, Kuwait.
Bioinorg Chem Appl. 2008;2008:479897. doi: 10.1155/2008/479897.
A new series of Zn(2+), Cu(2+), Ni(2+), and Co(2+) complexes of N(1)-methyl-2-(1H-1,2,3-benzotriazol-1-yl)-3-oxobutanethioamide (MBOBT), HL, has been synthesized and characterized by different spectral and magnetic measurements and elemental analysis. IR spectral data indicates that (MBOBT) exists only in the thione form in the solid state while 13C NMR spectrum indicates its existence in thione and thiole tautomeric forms. The IR spectra of all complexes indicate that (MBOBT) acts as a monobasic bidentate ligand coordinating to the metal(II) ions via the keto-oxygen and thiolato-sulphur atoms. The electronic spectral studies showed that (MBOBT) bonded to all metal ions through sulphur and nitrogen atoms based on the positions and intensity of their charge transfer bands. Furthermore, the spectra reflect four coordinate tetrahedral zinc(II), tetragonally distorted copper(II), square planar nickel(II), and cobalt(II) complexes. Thermal decomposition study of the complexes was monitored by TG and DTG analyses under N(2) atmosphere. The decomposition course and steps were analyzed and the activation parameters of the nonisothermal decomposition are determined. The isolated metal chelates have been screened for their antimicrobial activities and the findings have been reported and discussed in relation to their structures.
已合成并通过不同的光谱和磁性测量以及元素分析对一系列新的 Zn(2+)、Cu(2+)、Ni(2+) 和 Co(2+) 配合物进行了表征，这些配合物是 N(1)-甲基-2-(1H-1,2,3-苯并三唑-1-基)-3-氧代丁硫酰胺（MBOBT），HL 的。IR 光谱数据表明（MBOBT）在固态中仅以硫酮形式存在，而 13C NMR 谱表明其以硫酮和硫醚互变异构形式存在。所有配合物的 IR 光谱均表明（MBOBT）通过酮氧和硫醇硫原子以单齿双配位体的形式与金属（II）离子配位。电子光谱研究表明，（MBOBT）通过硫原子和氮原子与所有金属离子结合，这基于它们的电荷转移带的位置和强度。此外，这些光谱反映了四配位四面体锌（II）、四方形扭曲的铜（II）、正方形平面镍（II）和钴（II）配合物。通过在 N(2)气氛下的 TG 和 DTG 分析监测配合物的热分解。分析了分解过程和步骤，并确定了非等温分解的活化参数。已经对分离的金属螯合物进行了抗菌活性筛选，并根据其结构报告和讨论了结果。
