Immer Franz F, Aeschimann Rahel, Englberger Lars, Stadler Mario, Eckstein Friedrich S, Tevaearai Hendrik, Schmidli Jürg, Carrel Thierry P
Department of Cardiovascular Surgery, University Hospital, 3010 Bern, Switzerland.
J Heart Valve Dis. 2008 Jan;17(1):94-7; discussion 97.
Preservation of the aortic valve during the repair of acute type A aortic dissection (AADA) is a viable option to prevent lifelong oral anticoagulation. The study aim was to assess aortic valve function following resuspension and supracoronary ascending aortic grafting.
Among a collective of 210 consecutive patients undergoing surgery for AADA, 140 (66.7%) with resuspension of the aortic valve and supracoronary ascending graft were analyzed. Of these patients, 83 (59.3%) had a complete follow up (mean 61.2 +/- 40.8 months), with 65 of the subgroup (78.3%) being followed by computed tomography scanning and echocardiography.
Reoperation due to severe aortic valve regurgitation was required in seven patients (10.8%). The perioperative characteristics were similar in these patients; notably, no significant difference was evident with regards to the aortic annulus diameter and the severity of regurgitation at the time of surgery. The left ventricular mass index was significantly higher in patients requiring reoperation due to aortic valve regurgitation (219.3 +/- 146.6 versus 123.9 +/- 146.6 g/m2; p <0.05). None of the patients died as a result of reoperation.
The long-term functional results following resuspension of the aortic valve in AADA were very good. A close echocardiographic follow up was necessary, as reoperation of the aortic valve was required in more than 10% of the collective, with an average follow up of five years. Reoperation was mainly related to secondary dilatation of the aortic root.
在急性A型主动脉夹层(AADA)修复术中保留主动脉瓣是避免终身口服抗凝治疗的可行选择。本研究旨在评估主动脉瓣再悬吊及冠状动脉上升主动脉移植术后的主动脉瓣功能。
在连续210例行AADA手术的患者中,分析了140例(66.7%)接受主动脉瓣再悬吊及冠状动脉上升主动脉移植的患者。其中83例(59.3%)获得完整随访(平均61.2±40.8个月),亚组中的65例(78.3%)接受了计算机断层扫描和超声心动图检查。
7例患者(10.8%)因严重主动脉瓣反流需要再次手术。这些患者的围手术期特征相似;值得注意的是,手术时主动脉瓣环直径和反流严重程度无明显差异。因主动脉瓣反流需要再次手术的患者左心室质量指数显著更高(219.3±146.6对123.9±146.6 g/m²;p<0.05)。无一例患者因再次手术死亡。
AADA患者主动脉瓣再悬吊术后的长期功能结果非常好。由于超过10%的患者在平均五年的随访中需要进行主动脉瓣再次手术,因此密切的超声心动图随访是必要的。再次手术主要与主动脉根部的继发性扩张有关。