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头颈部滑膜肉瘤患者的治疗结果。

Treatment outcomes for patients with synovial sarcoma of the head and neck.

作者信息

Lee Nancy, Shin Edward

机构信息

Memorial Sloan-Kettering Cancer Center, Department of Radiation Oncology, NY, USA.

出版信息

Expert Rev Anticancer Ther. 2008 Mar;8(3):371-3. doi: 10.1586/14737140.8.3.371.

DOI:10.1586/14737140.8.3.371
PMID:18366285
Abstract

Evaluation of: Harb WJ, Luna MA, Patel SR, Ballo MT, Roberts DB, Sturgis EM. Survival in patients with synovial sarcoma of the head and neck: association with tumor location, size, and extension. Head Neck 29, 731-740 (2007). Synovial sarcoma of the head and neck occurs most commonly in males in their third decade of life. Synovial sarcoma of the head is rare, accounting for less than 10% of all head and neck sarcomas. Due to its rarity, there are very few publications on the treatment approach for these tumors. However, it is uniformly accepted that all head and neck synovial sarcomas should undergo complete surgical resection followed by postoperative radiation therapy in those at high risk for locoregional recurrence. In terms of chemotherapy, there are also emerging data on its effectiveness in the treatment of synovial sarcoma of the head and neck. The paper under evaluation reports a single institution's 36-year experience on the treatment of synovial sarcoma of the head and neck. This paper highlights the importance of a multidisciplinary approach in the treatment of this disease.

摘要

评估文献

哈布·W·J、卢娜·M·A、帕特尔·S·R、巴洛·M·T、罗伯茨·D·B、斯特吉斯·E·M。头颈部滑膜肉瘤患者的生存率:与肿瘤位置、大小及侵犯范围的关系。《头颈外科》29卷,731 - 740页(2007年)。头颈部滑膜肉瘤最常见于30岁左右的男性。头部滑膜肉瘤较为罕见,占所有头颈部肉瘤的比例不到10%。由于其罕见性,关于这些肿瘤治疗方法的出版物非常少。然而,人们一致认为,所有头颈部滑膜肉瘤患者均应接受完整的手术切除,对于有局部区域复发高风险的患者,术后还应进行放射治疗。在化疗方面,也有关于其对头颈部滑膜肉瘤治疗有效性的新数据。所评估的这篇论文报告了一家机构36年来对头颈部滑膜肉瘤的治疗经验。本文强调了多学科方法在治疗这种疾病中的重要性。

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