Sutton Bobbie Collett, Dunn S Terence, Landrum Jeff, Mielke Greg
Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
J Forensic Sci. 2008 Mar;53(2):472-5. doi: 10.1111/j.1556-4029.2008.00677.x.
Maternal hepatic rupture is a rare complication of pregnancy that can be fatal to both mother and child. This phenomenon is most often associated with preeclampsia/eclampsia and/or HELLP syndrome, which is defined by a collection of clinical features including hemolysis (H), elevated liver enzymes (EL), and a low platelet count (LP). These disease processes are typically identified and treated during pregnancy, often in the last trimester. The described case is unusual in that the decedent had no known history of preeclampsia/eclampsia or HELLP syndrome during this pregnancy, and she died suddenly several days postpartum of liver rupture with massive intraperitoneal hemorrhage following a routine cesarean section delivery and an uneventful hospital course. Similar cases are infrequent in the literature, which is reviewed in this report.
孕产妇肝破裂是一种罕见的妊娠并发症，对母婴均可能致命。这种现象最常与先兆子痫/子痫和/或HELLP综合征相关，HELLP综合征由溶血（H）、肝酶升高（EL）和血小板计数低（LP）等一系列临床特征所定义。这些疾病过程通常在孕期被识别和治疗，多在妊娠晚期。所描述的这例病例不同寻常，因为死者在此次妊娠期间没有已知的先兆子痫/子痫或HELLP综合征病史，且在剖宫产分娩过程顺利及住院期间情况平稳后，产后数天突然死于肝破裂伴大量腹腔内出血。文献中类似病例很少见，本报告对此进行了综述。
