Buyse S, Durand F, Joly F
Service d'Hépatologie--Pôle des Maladies de l'Appareil Digestif, AP-HP, Hôpital Beaujon, Université Paris-7, 100 Boulevard du Général-Leclerc, 92100 Clichy, France.
Gastroenterol Clin Biol. 2008 Mar;32(3):265-73. doi: 10.1016/j.gcb.2007.12.023. Epub 2008 Mar 25.
The liver plays a key role in the metabolism of nutrients. Therefore, liver failure is often associated with malnutrition. It is well-established that malnutrition is an independent prognostic factor in patients with cirrhosis and liver failure. Since standard anthropometric and biological indexes are associated with liver dysfunction, nutritional assessment is difficult in patients with cirrhosis. In this review, we explain the various causes and mechanisms leading to malnutrition in cirrhosis. We also describe reliable methods used to assess the nutritional condition of these patients. Finally, we stress the importance of nutritional care in cirrhosis and liver dysfunction, describing its specific characteristics and indications.
肝脏在营养物质的代谢中起着关键作用。因此,肝衰竭常与营养不良相关。众所周知,营养不良是肝硬化和肝衰竭患者的一个独立预后因素。由于标准人体测量和生物学指标与肝功能障碍有关,肝硬化患者的营养评估较为困难。在这篇综述中,我们解释了导致肝硬化患者营养不良的各种原因和机制。我们还描述了用于评估这些患者营养状况的可靠方法。最后,我们强调了肝硬化和肝功能障碍患者营养护理的重要性,并描述了其具体特点和适应证。