Rivera Irigoin Robin, Abilés Jimena
Servicio de Aparato Digestivo, Hospital Costa del Sol, Marbella, Málaga, España.
Gastroenterol Hepatol. 2012 Oct;35(8):594-601. doi: 10.1016/j.gastrohep.2012.03.001. Epub 2012 May 30.
Given the liver's multiple synthetic, regulatory and detoxifying functions, one of the characteristics accompanying severe hepatocellular dysfunction is the presence of malnutrition. This disorder is highly frequent in liver cirrhosis, even in the relatively early stages of the disease. Independently of the cause of the cirrhosis, poor nutritional status is associated with a worse prognosis and therefore early intervention to correct nutrient deficiency can prolong life expectancy, improve quality of life, reduce complications and increase the probability of successful transplantation. The present article reviews current knowledge of the diagnosis and management of malnutrition in patients with cirrhosis. Special attention is paid to the concept of the late evening snack and its characteristics, composition and probable benefits in the course of the disease.
鉴于肝脏具有多种合成、调节和解毒功能，严重肝细胞功能障碍所伴随的特征之一是营养不良。这种病症在肝硬化中非常常见，甚至在疾病的相对早期阶段也是如此。无论肝硬化的病因如何，营养状况不佳都与较差的预后相关，因此早期干预以纠正营养缺乏可延长预期寿命、改善生活质量、减少并发症并增加成功移植的可能性。本文综述了目前关于肝硬化患者营养不良诊断和管理的知识。特别关注了夜宵的概念及其特征、成分以及在病程中可能带来的益处。
