Fleisher Jay M, Lou Jennie Q, Farrell Maria
Nova Southeastern University, College of Osteopathic Medicine, Fort Lauderdale, FL 33328, USA.
J Community Health. 2008 Aug;33(4):179-82. doi: 10.1007/s10900-008-9090-z.
Breast cancer is the most common cancer in women, accounting for nearly 30% of all female cancers. Breast cancer is the second leading cause of cancer mortality in women in the US. During the last two decades, the benefits of early detection, early intervention, and postoperative treatment have resulted in decreased breast cancer mortality in the US general population. However, the distribution of breast cancer mortality varies among geographic regions of the US. The reasons for this variation remain largely unknown. We choose to look for a possible association between the numbers of physicians in each city within the State of Florida and breast cancer survival among women aged 40+ residing in that particular city. Using Cox Proportionate Hazard Modeling, we found a direct association between the number of physicians practicing in a particular city and breast cancer survival in that particular city (P=0.0153), while controlling for other known risk factors affecting survival. To our knowledge, this is the first study to report an association between physician supply and cancer survival within defined geographic areas. This association shows as physician density consistently dropped in a defined geographic area so did time of survival among women with breast cancer.
乳腺癌是女性中最常见的癌症,占所有女性癌症的近30%。乳腺癌是美国女性癌症死亡的第二大主要原因。在过去二十年中,早期检测、早期干预和术后治疗的益处已导致美国普通人群中乳腺癌死亡率下降。然而,乳腺癌死亡率的分布在美国各地区之间存在差异。这种差异的原因在很大程度上仍然未知。我们选择研究佛罗里达州各城市的医生数量与居住在该特定城市的40岁及以上女性的乳腺癌生存率之间可能存在的关联。使用Cox比例风险模型,我们发现在控制影响生存的其他已知风险因素的同时,特定城市执业的医生数量与该特定城市的乳腺癌生存率之间存在直接关联(P = 0.0153)。据我们所知,这是第一项报告在特定地理区域内医生供应与癌症生存率之间存在关联的研究。这种关联表现为,在特定地理区域内,随着医生密度持续下降,乳腺癌女性的生存时间也随之下降。