使用脂质体进行癌症药物递送。

Drug delivery in cancer using liposomes.

作者信息

Dass Crispin R

机构信息

Department of Orthopaedics, St. Vincent'ps Hospital Melbourne, Fitzroy, Vic., Australia.

出版信息

Methods Mol Biol. 2008;437:177-82. doi: 10.1007/978-1-59745-210-6_9.

DOI:10.1007/978-1-59745-210-6_9

PMID:18369969

Abstract

There are various types of liposomes used for cancer therapy, but these can all be placed into three distinct categories based on the surface charge of vesicles: neutral, anionic and cationic. This chapter describes the more rigorous and easy methods used for liposome manufacture, with references, to aid the reader in preparing these formulations in-house.

摘要

有多种类型的脂质体用于癌症治疗，但根据囊泡的表面电荷，这些脂质体都可分为三个不同的类别：中性、阴离子型和阳离子型。本章介绍了用于制备脂质体的更为严谨且简便的方法，并附有参考文献，以帮助读者在内部制备这些制剂。