Casale Pasquale, Meyers Kevin, Kaplan Bernard
Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania 19107, USA.
J Endourol. 2008 May;22(5):991-3. doi: 10.1089/end.2007.0359.
To present our medium-term experience with laparoscopic renal denervation and nephropexy for autosomal dominant polycystic kidney disease (ADPKD)-related pain in the pediatric patient.
Twelve patients aged 8 to 19 years (mean age 12.4 years) with ADPKD presented with chronic pain refractory to narcotic analgesics. These 12 patients underwent laparoscopic renal denervation of 16 kidneys.
Mean operative time was 152 minutes and mean hospital stay was 2.17 days. All patients were pain-free at discharge and remain pain-free at a mean follow-up of 25.5 months. Three adolescent patients each had an episode of flank pain. One was associated with pyelonephritis, another with stones, and the third with trauma and a hematoma.
Laparoscopic renal denervation and nephropexy is a promising option for pediatric patients with uncontrolled ADPKD-related pain.
介绍我们对患有常染色体显性多囊肾病（ADPKD）相关疼痛的儿科患者进行腹腔镜肾去神经支配和肾固定术的中期经验。
12例年龄在8至19岁（平均年龄12.4岁）的ADPKD患者出现对麻醉性镇痛药难治的慢性疼痛。这12例患者对16个肾脏进行了腹腔镜肾去神经支配术。
平均手术时间为152分钟，平均住院时间为2.17天。所有患者出院时均无疼痛，在平均25.5个月的随访中仍无疼痛。3例青少年患者各有一次胁腹痛发作。1例与肾盂肾炎有关，另1例与结石有关，第3例与外伤和血肿有关。
腹腔镜肾去神经支配和肾固定术对于患有无法控制的ADPKD相关疼痛的儿科患者是一个有前景的选择。
