Blumenthal Kevin B, Sutherland Douglas E, Wagner Kristofer R, Frazier Harold A, Engel Jason D
Department of Urology, the George Washington University Hospital, Washington, District of Columbia 20037, USA.
Urology. 2008 Jul;72(1):158-61. doi: 10.1016/j.urology.2007.11.105. Epub 2008 Apr 18.
Recently, several large series of robot-assisted laparoscopic radical prostatectomy (RALP) have described a low incidence of bladder neck contractures (BNC). We have had a similar experience at our institution. Our objective is to describe our experience with BNC after RALP and a novel relationship to the use of Hem-o-lok Clips (HOLC).
We reviewed a database of patients who underwent RALP at our institution from January 2004 to September 2007 and identified patients with BNC or complications related to the use of HOLC. We performed a retrospective chart review to attempt to determine the cause of each BNC. We also performed a PubMed search and review of the Food and Drug Administration Manufacturer and User Facility Device Experience (MAUDE) database.
Of 524 patients undergoing RALP, 4 had a BNC develop, 2 of the BNCs were associated with HOLC migration and erosion into the vesicourethral anastomosis, and 1 was found to have HOLC migration within the bladder. A fifth patient had an anastomotic leak develop secondary to a HOLC that migrated into the bladder neck. Two similar cases of HOLC-related migration have been reported to MAUDE.
When early BNC or unexplained urinary retention occurs after RALP, one should have a high index of suspicion for migration of HOLC. Clip use should be minimized on tissue immediately adjacent to the anastomosis, and every effort should be made to retrieve loose clips after the procedure.
最近,有几篇关于机器人辅助腹腔镜根治性前列腺切除术(RALP)的大型系列报道称膀胱颈挛缩(BNC)的发生率较低。我们机构也有类似的经验。我们的目的是描述我们在RALP术后处理BNC的经验以及与使用Hem-o-lok夹(HOLC)的一种新关系。
我们回顾了2004年1月至2007年9月在我们机构接受RALP的患者数据库,确定患有BNC或与使用HOLC相关并发症的患者。我们进行了回顾性病历审查,试图确定每个BNC的原因。我们还进行了PubMed检索并查阅了美国食品药品监督管理局的制造商和用户设施设备经验(MAUDE)数据库。
在524例行RALP的患者中,有4例发生了BNC,其中2例BNC与HOLC迁移至膀胱尿道吻合口并侵蚀有关,1例发现HOLC在膀胱内迁移。第五例患者因HOLC迁移至膀胱颈继发吻合口漏。有两例类似的与HOLC相关的迁移病例已上报至MAUDE。
当RALP术后早期出现BNC或不明原因的尿潴留时,应高度怀疑HOLC迁移。应尽量减少在紧邻吻合口的组织上使用夹子,并且术后应尽一切努力取出松动的夹子。