先前采用负压封闭引流(VAC)治疗后开放性四肢骨折的延迟皮瓣覆盖——效果更差还是值得一试?
Delayed flap coverage of open extremity fractures after previous vacuum-assisted closure (VAC) therapy - worse or worth?
作者信息
Steiert Andreas E, Gohritz Andreas, Schreiber Thomas C, Krettek Christian, Vogt Peter M
机构信息
Department of Plastic and Reconstructive Surgery, Hannover Medical School, Hannover, Germany.
出版信息
J Plast Reconstr Aesthet Surg. 2009 May;62(5):675-83. doi: 10.1016/j.bjps.2007.09.041. Epub 2008 Mar 25.
BACKGROUND
Controversy remains regarding timing in the management of complex traumatic lower extremity defects. Many authors recommend a definitive bony and soft tissue reconstruction within a critical period of 72 h, yet in many patients this may be impossible due to concomitant injuries or delayed referral. However, little data are available on the results of delayed flap reconstruction of complex traumatic extremity defects, especially using new technologies of wound coverage such as vacuum-assisted closure (VAC((R))) therapy which may reduce the disadvantages of conventional open wound therapy prior to a subsequent flap reconstruction.
METHODS
We retrospectively analysed the soft tissue reconstructions in 43 open extremity fractures during a 4-year period with special regard to complications, overall flap loss and wound infection.
RESULTS
A total of 29 male and 13 female patients with 33 open fractures of the lower and 10 of the upper extremity were included. All patients had been referred from a trauma centre at a mean interval of 19 days (range 1-96 days) after the trauma event with temporary VAC((R)) of their wounds after initial fracture fixation and initial debridement of necrotic tissue. Flap reconstruction was thus only possible later than 72 h and definitive wound closure was achieved at a mean time of 28 days (range 3-106 days). Overall, three pedicled flaps were lost and one of 38 microsurgical free flaps (2.6%) underwent necrosis, the cause of which was unrelated to treatment delay.
CONCLUSIONS
According to this study, the flap reconstructions performed beyond the frequently quoted critical interval yielded similar results to those of immediate reconstruction within the first 3 days, as reported in the literature. This strategy is in accordance with the principles of 'Damage Control Orthopaedics (DCO)' and may reduce the importance of emergency reconstructions, especially in poly-traumatised patients.
背景
复杂创伤性下肢缺损的治疗时机仍存在争议。许多作者建议在72小时的关键期内进行确定性的骨和软组织重建,但在许多患者中,由于合并伤或转诊延迟,这可能无法实现。然而,关于复杂创伤性肢体缺损延迟皮瓣重建的结果,尤其是使用新型伤口覆盖技术如负压封闭引流(VAC((R)))治疗的数据很少,这种技术可能会减少后续皮瓣重建前传统开放伤口治疗的弊端。
方法
我们回顾性分析了43例开放性肢体骨折患者在4年期间的软组织重建情况,特别关注并发症、总体皮瓣丢失和伤口感染。
结果
共纳入29例男性和13例女性患者,其中33例为下肢开放性骨折,10例为上肢开放性骨折。所有患者均从创伤中心转诊而来,创伤事件发生后的平均间隔时间为19天(范围1 - 96天),在初始骨折固定和坏死组织初步清创后,伤口进行了临时VAC((R))治疗。因此,皮瓣重建只能在72小时后进行,平均在28天(范围3 - 106天)实现确定性伤口闭合。总体而言,3个带蒂皮瓣丢失,38个显微外科游离皮瓣中有1个(2.6%)发生坏死,其原因与治疗延迟无关。
结论
根据本研究,在经常提及的关键间隔时间之后进行的皮瓣重建,其结果与文献报道的前3天内立即重建的结果相似。这种策略符合“损伤控制骨科(DCO)”的原则,可能会降低急诊重建的重要性,尤其是在多发伤患者中。